After nerve injury, the protein complex mTORC1 takes over an important function in skeletal muscle to maintain the neuromuscular junction, the synapse between the nerve and muscle fiber. Researchers at the University of Basel’s Biozentrum have now shown that the activation of mTORC1 must be tightly balanced for a proper response of the muscle to
THURSDAY, Nov. 29, 2018 — Connections between different areas of the brain are sustained longer than usual in people with autism, perhaps explaining some of their symptoms, a new study suggests. It’s possible these prolonged connections make it difficult for the brain to switch from one activity to another, the researchers said. “People with autism
For decades, scientists have examined how regions of the brain communicate to understand autism. Researchers at University of Utah Health believe the symptoms of autism may result from sustained connections between regions of the brain. The details of their study are available November 16 in the journal JAMA Network Open. “People with autism do not
As the brain grows and develops, nerve cells must make connections between one another in order to function properly. Brain cells are tightly packed together, so each cell might touch hundreds or thousands of other cells, and yet those cells only make stable and strong connections with a fraction of those neighboring cells. Researchers have
For decades, the neuroscience community has been baffled by the existence of dense connections in the brain that seem to be going “backwards.” These connections, which span extensively across distant areas of the neocortex, are clearly conveying important information. But until now, the organization of the connections, and therefore their possible role, was largely unknown.