Tag: Crohn’s Disease

Bowel preparation for colon surgery unnecessary, study suggests

In recent decades, patients in Europe coming in for colectomies, or surgical procedures targeted at the colon, have not been routinely subjected to what is known as bowel preparation, where the bowel is emptied before the operation. In the United States , on the other hand, cleansing the bowel is relatively common. Several extensive retrospective

Potential treatment for NEC in preemies: Scientists discover how to prevent disease in an animal model, offer a new direction toward treatment strategy

Cutting-edge discovery in the lab of Catherine Hunter, MD, from Stanley Manne Children’s Research Institute at Ann & Robert H. Lurie Children’s Hospital of Chicago offers a new direction toward treatment of necrotizing enterocolitis (NEC) — a devastating intestinal emergency that occurs in up to 10 percent of premature infants. NEC is a leading cause

Study offers promise for preventing necrotizing enterocolitis in preemies: Preventing inflammatory white blood cell infiltration in the intestine decreases development of necrotizing enterocolitis in animal model

Researchers at Stanley Manne Children’s Research Institute at Ann & Robert H. Lurie Children’s Hospital of Chicago, and colleagues, discovered a promising direction toward understanding the development of necrotizing enterocolitis (NEC), a devastating intestinal disease commonly affecting premature infants, in order to treat it. Studying the early cellular events leading to NEC in a mouse

Inflammatory bowel disease linked to prostate cancer: Men with inflamed guts are four to five times at risk for prostate cancer

Men with inflammatory bowel disease have four to five times higher risk of being diagnosed with prostate cancer, reports a 20-year study from Northwestern Medicine. This is the first report to show men with inflammatory bowel disease have higher than average PSA (prostate-specific antigen) values, and this group also has a significantly higher risk of

What Is Inflammatory Bowel Disease?

Inflammatory bowel disease (IBD) is a condition that involves chronic inflammation in all or part of the digestive tract. Often painful and debilitating, IBD can lead to life-threatening complications as well as increase the risk for colon cancer. More than 3 million people have IBD, according to a recent government survey. The two most common

People with Psoriasis More Likely to Develop Certain Gut Disorders

People with psoriasis may be at greater risk of developing certain gut disorders, a new study finds. The research discovered that people with psoriasis, an inflammatory skin condition, were about two times more likely to develop the gut disorders Crohn's disease and ulcerative colitis compared to people in the general population. Both Crohn's disease and

A study points to new therapeutic targets for tumors associated with chronic inflammation: A new study demonstrates that myeloid cells use p38 protein signalling to support inflammation-associated colon cancer

Scientists headed by ICREA researcher Angel R. Nebreda at the Institute for Research in Biomedicine (IRB Barcelona) report a new mechanism that contributes to the development of inflammation-associated colon cancer and points to new therapeutic targets. The study has been published in the journal EMBO Molecular Medicine. More than a million people worldwide are diagnosed

How IBD Messes With Your Period, Pregnancy, and Sex Life

If you have inflammatory bowel disease (IBD) and you think it’s messing with your menstrual cycle, your pregnancy, your menopause, and even your sex life, you’d be…right. Women have all the luck, eh? IBDs affect both women and men, but as often seems to be the case, women experience unique challenges with it. For a

The Link Between IBD and Anxiety

Chalk another one up to the mind-body connection. Researchers out of the University of Toronto have discovered that people who have inflammatory bowel disease — inflammatory conditions of the colon and small intestine– like Crohn’s disease or ulcerative colitis have twice the odds of having a generalized anxiety disorder at some point in their lives

Gut check: Metabolites shed by intestinal microbiota keep inflammation at bay: Researchers find inflammatory response in fatty liver disease is reduced by two tryptophan metabolites from gut bacteria

Researchers at Tufts University have elucidated a mechanism by which the “good” bacteria that reside in our gastrointestinal tract can help protect us from inflammation, and how their disruption (dysbiosis) can increase the susceptibility of the liver to more harmful forms of disease. Their study, now available in the journal Cell Reports, identified two key