Tag: dengue

Yellow fever was the first human disease to have a licensed vaccine and has long been considered important to understanding how epidemics break out and should be combated. It was introduced to the Americas in the 17th century, and high death rates have resulted from successive outbreaks since then. Epidemics of yellow fever were associated

A team of researchers has discovered an antibody that blocks the ability of the dengue virus to cause disease in mice. The findings open the potential for developing effective treatments and designing a vaccine for dengue and similar diseases. Dengue virus, a member of a group of viruses called flaviviruses, causes 50 to 100 million

Mosquitoes are more likely to acquire the dengue virus when they feed on blood with low levels of iron, researchers report in the 16 September issue of Nature Microbiology. Supplementing people’s diets with iron in places where both iron deficiency anemia and dengue fever are a problem could potentially limit transmission of the disease, but

Researchers led by Duke-NUS Medical School have discovered that tryptase, an enzyme in human cells that acts like scissors to cut up nearby proteins, is responsible for blood vessel leakage in severe dengue hemorrhagic fever. The finding suggests a possible new treatment strategy using the tryptase inhibitor, nafamostat mesylate, for severe dengue disease—a potentially fatal

As many as a billion people could be newly exposed to disease-carrying mosquitoes by the end of the century because of global warming, says a new study that examines temperature changes on a monthly basis across the world. Scientists say the news is bad even in areas with only a slight risk of having a

Women who have previously been infected with dengue virus may be at risk for increased damage to their fetuses and placentas if they should later become infected with the Zika virus, researchers from the Department of Microbiology at the Icahn School of Medicine at Mount Sinai report. This study is the first to report a

Previous infection with dengue virus may protect children from symptomatic Zika, according to a study published January 22 in the open-access journal PLOS Medicine by Eva Harris of the University of California, Berkeley, and colleagues. Zika virus emerged in northeast Brazil in 2015 and spread rapidly across the Americas, affecting populations that have been largely

Dengue and Zika viruses are closely related and carried by mosquitos. In infested subtropical and tropical areas, dengue transmission often precedes Zika virus (ZIKV) infection, suggesting that women who previously acquired dengue immunity may be bitten by ZIKV-carrying mosquitoes during pregnancy. Whether that mother’s prior dengue immunity would protect her unborn baby from devastating brain

Dengue, a mosquito-borne RNA virus, is one of the most serious and rapidly spreading arboviral diseases in the world. Now, researchers reporting in PLOS Neglected Tropical Diseases have provided the first baseline data on the prevalence and risk factors of the virus in Ethiopia. It is estimated that more than 390 million dengue virus (DENV)

Using an original mathematical and statistical analysis method, a team of scientists from the Institut Pasteur partnered with researchers from the United States and Thailand to analyze a Thai cohort that has long been a focus of study for dengue specialists, and obtained new information that should help identify individuals at risk of infection. By

People showing virtually no symptoms are likely the primary source of dengue fever, according to new research published in PLOS Pathogens. Nearly 400 million people each year are infected with dengue virus, which is transmitted through mosquitoes. The study estimates that more than 80 percent of dengue virus infections are attributable to individuals with mild

A traditional herbal remedy for the dangerous tropical disease ‘dengue fever’ could be turned into a pill to treat patients thanks to groundbreaking research by scientists at the University of Nottingham’s Malaysia Campus (UNMC).  Papaya leaf juice has for a long time been used in some areas of India and South East Asia as a