Tag: drugs

California could become the first state with its own prescription drug label under a proposal that Gov. Gavin Newsom unveiled Thursday in a bid to lower prices by increasing competition in the generic market. Newsom wants the nation’s most populous state, home to nearly 40 million people, to contract with generic drug companies to make

A newly published paper in PNAS details a research breakthrough that provides a promising starting point for scientists to create drugs that can cure C. diff—a virulent health care-associated infection that causes severe diarrhea, nausea, internal bleeding, and potentially death. The bacteria affects roughly half-a-million Americans and causes nearly 15,000 deaths in the U.S. annually.

Tesco, Sainsbury’s and ASDA recall own-brand versions of the heartburn and indigestion drug Zantac over fears they are contaminated with a cancer-causing chemical The supermarket products were among 13 new additions to an ongoing recall Products in the UK and US have been taken off shelves due to contamination Ranitidine drugs are thought to have

Researchers at The Ohio State University Comprehensive Cancer Center—Arthur G. James Cancer Hospital and Richard J. Solove Research Institute (OSUCCC—James) report a discovery that helps scientists understand why some tumors lack immune cell infiltration and are therefore unresponsive to newer PD-1 targeted therapies. PD-1 is a checkpoint protein on T cells, a type of immune

Biomedical engineers at Duke University have developed a method to address failures in a promising anti-cancer drug, bringing together tools from genome engineering, protein engineering and biomaterials science to improve the efficacy, accuracy and longevity of certain cancer therapies. Using a combination of CRISPR-based targeting, a protein “depot” that allows for sustained release of the

A team of Brown University researchers has developed a new computer model that simulates the way red blood cells become misshapen by sickle cell disease. The model, described in a paper published in Science Advances, could be useful in the preclinical evaluation of drugs aimed at preventing the sickling process. “There are currently only two

Officials recall MORE batches of two drugs for Parkinson’s and epilepsy amid fears they were stored wrongly and could be ineffective Neupro and Vimpat are being recalled by the UK’s medicines regulator  There are concerns they were wrongly stored and may not work properly There was a recall of the same drugs from a different

A new computational framework has revealed key differences between four rheumatoid arthritis medications and their impact on biological pathways in mice. Niki Karagianni of Biomedcode Hellas SA, Greece, and colleagues present their new approach and findings in PLOS Computational Biology. People with rheumatoid arthritis often receive medications that target and inhibit Tumor-Necrosis Factor (TNF), a

Drugs used to target HER2-positive invasive breast cancer may also be successful in treating women in the first stages of the disease, researchers at The University of Nottingham have discovered. The findings, published in the British Journal of Cancer and led by experts in the University’s School of Medicine, suggest that extending anti-HER2 drugs to

Researchers have long-known that abused children are at higher risk of adolescent drug use. But a new study shows that having a father in the picture serves as a “protective factor,” helping to mitigate early childhood trauma. Researchers from the Jack, Joseph, and Morton Mandel School of Applied Social Sciences at Case Western Reserve University,

Treatments that prevent recurrence of types of stroke and dementia caused by damage to small blood vessels in the brain have moved a step closer, following a small study. The drugs—called cilostazol and isosorbide mononitrate—are already used to treat other conditions, such as heart disease and angina. This is the first time they have been

Precision cancer drugs called PARP inhibitors have a previously unknown ability to boost the immune system, and could help many more patients benefit from immunotherapy, a new study reveals. Scientists found that PARP inhibitors sparked a powerful immune response when used against cancer cells with weaknesses in repairing their DNA. The study changes our understanding

Dr. Alan Green’s patients travel from around the country to his tiny practice in Queens, N.Y., lured by the prospect of longer lives. Over the past two years, more than 200 patients have flocked to see Green after learning that two drugs he prescribes could possibly stave off aging. One 95-year-old was so intent on

Here are 11 drugs that have been known to cause excessive hair loss as a side effect. 1) Cholesterol-lowering medications — atorvastatin and simvastatin Atorvastatin (Lipitor) and simvastatin (Zocor) belong to a group of cholesterol-lowering medications known as “statins”. Have hair loss is a reported side effect of both drugs. The newer statin, rosuvastatin (Crestor),

Scientists have identified an enzyme that is a “master regulator” of kidney function that if excessively suppressed, can trigger renal failure. Their findings have implications for the use of existing drugs and the development of new pharmaceuticals. As reported in Nature Communications, a global research team led by the University of Bristol studied how the

Cancer drugs are able to halt life-threatening bacterial lung infections in mouse models by promoting lung repair, researchers at Duke Health have found. Reporting in this week’s Proceedings of the National Academy of Sciences, the research team said that if the findings are confirmed in human studies, the drugs could point to a new weapon

Heroin is the deadliest of drugs for decades and it leads the drug-related death statistics, by a large margin. The reason is that opioids, substances which are the drug of the opium Poppy, similar to that naturally occur in the brain. And you intoxicate not only that, you can also dampen important functions in the

The issue of drug use and harm is one of the most compelling challenges of the current era. The so-called “war on drugs,” in which the UN has tried to stamp out recreational drug use through attacking drug suppliers and drug users, has been fought for over 40 years at great economic social and human

Cancer tissue cells are divided into two major groups: cancer cells and cancer stem cells (CSCs). CSCs are related to cancer progression and dissemination, so it’s necessary to eradicate CSCs in order to cure cancer. However, because CSCs are resistant to chemotherapy and radiotherapy, cancer is refractory. A research group from Osaka University, in collaboration

TUESDAY, July 17, 2018 — A new draft guideline from the U.S. Food and Drug Administration suggests Americans could get widely used prescription medicines for cholesterol, high blood pressure, asthma, and migraine headaches without having to see a doctor. The FDA says patients could use a mobile-phone app to help determine if they’re able to