Tag: drugs

TUESDAY, July 17, 2018 — Pivotal trials supporting U.S. Food and Drug Administration approvals granted Breakthrough Therapy designation often lack randomization, double-blinding, and control groups, according to a research letter published in the July 17 issue of the Journal of the American Medical Association. Jeremy Puthumana, from the Yale University School of Medicine in New

Lesbian, gay, bisexual or questioning (LGBQ) teens are at substantially higher risk of substance use than their heterosexual peers, according to a new study led by San Diego State University researchers and published in the American Journal of Public Health. As part of the most recent National Youth Risk Behavior Survey—the largest national survey on

Among the most serious consequences of the opioid epidemic is the spread of hepatitis C among injecting drug users. A major new study shows that if a hepatitis C vaccine were successfully developed, it would dramatically reduce transmission of hepatitis C among drug users—even though it’s unlikely such a vaccine would provide complete immunity. The

An increased use of clot-busting medicines prevented 4,000 strokes in England between 2015 and 2016, according to new research. The drugs were given to patients who were suffering from an irregular heartbeat called atrial fibrillation (AF) which can result in a five-fold increased risk of a stroke, compared to people who do not have the

I’ve been inhaling potent “skunk” cannabis every day for months and it’s making me sick. I should explain, it’s not me who’s got a drug habit, but a neighbour. He gets home from work at 5am, skins-up a spliff and the sickly aroma seeps down the corridor and under the door into my joint. Ironically

Purdue University researchers have identified  a new compound that in preliminary testing has shown itself to be as effective as antibiotics approved by the Food and Drug Administration to treat life-threatening infections while also appearing to be less susceptible to bacterial resistance. The compound, called F6, has been potent against antibiotic-resistant pathogens such as methicillin-resistant

To my mind, criminalisation of illegal drugs is inhumane and counterproductive. The “war on drugs” hasn’t and doesn’t work. It’s high time we shifted our focus from criminal punishment to ­public health. If this offends your ideology I should tell you that the Royal College of ­Physicians, the British Medical ­Association, The British Medical Journal

Scientists have uncovered a completely new way to make cancers sensitive to treatment—by targeting antenna-like structures on cells. Their study found that drug-resistant cancer cells have more and longer antennae than those which are killed by treatment. Blocking the growth of antennae reactivated a range of cancer treatments that had stopped working, the team at

Getting a new pharmaceutical from an idea in the chemistry lab to market takes many years and billions of dollars. Each year just several dozen new drugs are approved for use in the United States. Human “organs-on-chips” are leading a revolution in drug safety testing. These devices use human cells to model the structure and

A new anti-cancer drug may be effective against a wider range of cancers than previously thought. Using a mouse model and samples taken from cancer patients, a team from the Technical University of Munich (TUM) has shown that a new class of drugs known as SHP2 inhibitors is also effective against aggressive, hard-to-treat tumors such

Wake Forest Institute for Regenerative Medicine (WFIRM) scientists have developed a 3-D brain organoid that could have potential applications in drug discovery and disease modeling. This is the first engineered tissue equivalent to closely resemble normal human brain anatomy, containing all six major cell types found in normal organs including, neurons and immune cells. In

Growing levels of resistance to antifungal treatments could lead to increased disease outbreaks and affect food security around the world. An international team, led by researchers from Imperial College London and the University of Exeter, warns that improvements are needed in how existing drugs are used, as well as an increased focus on the discovery

Nurses across Britain are getting high and passing out while treating prisoners who have taken the drug Spice. Medical staff are being put at risk by the epidemic in use of the potent synthetic cannabis in jails with some treating 50 inmates a week. The Royal College of Nursing is calling for more protection for

The majority of patients eligible for cancer immunotherapy drugs known as checkpoint inhibitors received treatment within a few months of FDA approval, according to a new Yale-led study. The finding suggests that cancer immunotherapies are adopted at a much quicker pace than is typical for newly approved medical treatments, the researchers said. However, patients receiving

How people fitted with gastric bands are turning to drink and drugs after surgery because they can’t eat There’s an attitude among some surgeons that the operation ‘fixed’ the patient However the patient may have been over-eating to deal with their issues Therefore they are dealing with their inability to eat by turning to drugs

Can you REALLY change your brain with drugs, supplements and apps? Experts break down the science behind mind-boosting fads Healthy people of all ages are seeking cognitive enhancement for personal, athletic, academic, and professional gains, and to keep function into old age  Siobhan Schabrun, a brain plasticity researcher at Western Sydney University, explains what works

For most people, it’s better to start taking drugs for multiple sclerosis (MS) early on rather than letting the disease run its course, according to a new guideline for treating MS from the American Academy of Neurology. The guideline is published in the April 23, 2018, online issue of Neurology, the medical journal of the