Tag: expression

Gene expression pattern pinpoints high-risk colorectal cancer

A new technique could dramatically reduce the number of colorectal cancer patients who unnecessarily undergo major surgery to remove tumors, instead of a minimally invasive procedure. Biomedical scientist Xin Wang of City University of Hong Kong and colleagues have used machine learning to identify a gene expression pattern, or signature, associated with colorectal cancer spreading,

A deep-dive into the impact of arthritis drugs on gene expression

A new computational framework has revealed key differences between four rheumatoid arthritis medications and their impact on biological pathways in mice. Niki Karagianni of Biomedcode Hellas SA, Greece, and colleagues present their new approach and findings in PLOS Computational Biology. People with rheumatoid arthritis often receive medications that target and inhibit Tumor-Necrosis Factor (TNF), a