Tag: Genetic

Cocaine addiction: Impact of genetic mutations elucidated

Cocaine addiction is a chronic disorder with a high rate of relapse for which no effective treatment is currently available. Scientists from the Institut Pasteur, the CNRS, Inserm and the Paris Public Hospital Network (AP-HP) recently demonstrated that two gene mutations involved in the conformation of nicotinic receptors in the brain appear to play a

Study shows the importance of good cardiovascular health in preventing type 2 diabetes, regardless of genetic risk

New research presented at this year’s annual meeting of the European Association for the Study of Diabetes (EASD), held online this year, shows the importance of good cardiovascular health in preventing type 2 diabetes (T2D) among middle-aged individuals, regardless of any genetic predisposition they may have towards developing the disease. The study was conducted by

Genetic background may affect adaptions to aging

How we adapt to aging late in life may be genetically influenced, according to a study led by a psychologist at the University of California, Riverside. The research, published in Aging Cell, has implications for how epigenetic factors relate to aging. Epigenesis is a process in which chemicals attached to DNA control its activity. Epigenetic

Genetic tests may differ in their interpretation of certain variants

(HealthDay)—Different genetic test interpretations have been identified for genetic variants, and some of these can impact patient management, according to a research letter published online June 30 in the Annals of Internal Medicine. Jeffrey A. SoRelle, M.D., from the University of Texas Southwestern Medical Center in Dallas, and colleagues examined the prevalence of different interpretations

How do genetic differences affect the risk of bipolar disorder?

So concluded the scientists at the Picower Institute for Learning and Memory at Massachusetts Institute of Technology (MIT) in Cambridge who carried out the novel research. In previous work, they had already shown that a protein called candidate plasticity gene 2 (CPG2) helps to regulate the strength of synapses in brain circuits. Synapses are the

Four honored for genetic research and developing anesthetic

Four scientists have won prestigious medical awards for genetics research and development of a widely used anesthetic nicknamed “milk of amnesia.” Winners of the $250,000 awards from the Albert and Mary Lasker Foundation were announced Tuesday. The prizes will be presented later this month in New York. The clinical medicine award went to John B.

Attending Surgeon Influences Genetic Testing in Breast Cancer

WEDNESDAY, July 11, 2018 — The attending surgeon is associated with variation in the receipt of genetic testing after breast cancer diagnosis, according to a study published online July 3 in JAMA Surgery. Steven J. Katz, M.D., M.P.H., from the University of Michigan Medical School in Ann Arbor, and colleagues examined the correlation of attending

Blood mutations could contaminate genetic analyses of tumors

Genetic mutations in blood cells that have made their way into tumors could be red herrings that mislead physicians looking for genetic changes in tumors that are helping to drive the cancer. This finding is significant because physicians could make misinformed treatment decisions. At the 2018 American Society of Clinical Oncology Annual Meeting this week,