An oxysterol that accumulates in the eye with age can transform choroidal endothelial cells; interfering with the process might help patients with treatment-resistant age-related macular degeneration. The latest research from the laboratory of John A. Moran Eye Center physician-scientist Mary Elizabeth Hartnett, MD, reveals how an oxidized form of cholesterol can change choroidal endothelial cells
Researchers from Karolinska Institutet and Gothenburg University have investigated a potential new drug target for the rare genetic disorder Hutchinson-Gilford progeria syndrome that causes accelerated aging in children. The findings in mice are published in the scientific journal eLife and may aid in the development of more effective treatments for this fatal condition. Hutchinson-Gilford progeria
A major clinical trial in Canada shows that an inexpensive anti-inflammatory drug called colchicine can significantly reduce the risk of complications and death from COVID-19, bringing “important hope” to sufferers, the lead researcher said Sunday. Jean-Claude Tardif, head of the Montreal Heart Institute (ICM), led the study named “Colcorona,” whose preliminary results were published Friday
QIMR Berghofer researchers have developed a way of testing whether or not COVID-19 patients’ immune systems are gearing up to fight the virus that causes the deadly disease. They hope the discovery could be used to identify early on which patients’ immune systems are not responding appropriately, and who might therefore be at higher risk
An international consensus panel led by researchers from The Westmead Institute for Medical Research (WIMR) has highlighted the need to redefine Non-Alcoholic Fatty Liver Disease (NAFLD), and to name it Metabolic Associated Fatty Liver Disease (MAFLD). Researchers highlighted that the new terminology will better reflect its causes, and improve public health initiatives. MAFLD is a
Scientists from Trinity College Dublin have made an important discovery that could lead to more effective treatments for people living with multiple sclerosis (MS) and other autoimmune diseases such as psoriasis and rheumatoid arthritis. Their work highlights the significant potential of drugs targeting a specific immune molecule (IL-17) implicated in MS. The scientists, led by
Abby Lee Miller posted a new video to Instagram showing herself doing a plié and relevé out of her wheelchair. The Dance Moms star completes the standing ballet moves with the help of a walker. Abby lost her mobility following her Burkitt lymphoma diagnosis and undergoing spinal surgery last year. Abby Lee Miller is dancing
Breakthrough research has revealed a new drug that may prevent the spread of malaria, and also treat people suffering with the deadly parasitic disease. The findings, which were delivered by an international team of scientists led by the University of Glasgow and published today in Science, offer fresh hope in the global fight against malaria.
A new mental health app, designed to help manage negative emotions and periods of extreme anxiety for young people, could have a significant impact on reducing self-harm according to research. The ‘BlueIce’ app, developed in conjunction with patient groups by leading clinical psychologist Professor Paul Stallard, is now included in the national NHS app library.
For patients with Type 1 diabetes who don’t respond well to insulin or have other serious medical complications caused by their disease, pancreas transplantation offers hope for a cure. But obese candidates who need a pancreas transplant often are denied the procedure because of poor outcomes, including high rates of incision infections, which are linked
Tuberculosis (TB) is the leading cause of death in the world from a single infectious disease, causing more deaths than HIV/AIDS. In 2017, 10 million people developed TB disease globally and an estimated 1.6 million died. One of the biggest blocks to beating the epidemic is the growing resistance to drugs that have previously cured
Autoimmune diseases, including type 1 diabetes and multiple sclerosis, arise when the body’s immune cells attack itself. Current treatments eliminate these misfunctioning immune cells, but also destroy normal, protective immune cells, leaving patients susceptible to immune deficiency and opportunistic infections. Researchers at University of Utah Health have developed a new approach that targets the misfunctioning
FRIDAY, March 1, 2019 — It may be possible to restore brain cells damaged by Parkinson’s disease and reverse a patient’s condition, something no current treatment can do, according to British researchers who conducted potentially groundbreaking clinical trials. They cautioned the trial was small — just 41 patients — and the research is still in
Korean researchers have identified the inhibition of autophagy in microglia, brain immune cells. It is expected to help develop treatments for Alzheimer’s disease which occur due to the inhibition of autophagy. Alzheimer’s disease (AD) is the most representative degenerative brain disease, accounting for 60 to 80 percent of all dementia cases. In search for new
Hope for children left paralysed by mysterious condition which prompted a Government investigation as pioneering surgery is proven to restore muscle function Nerve grafts could be used to bring children’s paralysed muscles back to life It is being tried in patients with acute flaccid myelitis/paralysis, which is rising At least 28 Britons and 168 Americans
Hope for epileptics as scientists discover implanting stem cells into the brain could stop seizures The treatment, tested on rats, would modify the patient’s own skin cells Stem cell treatment led to 70% fewer seizures in the months following It inhibits excitement in the hippocampus, where epileptic seizures can start Currently, surgery to remove the hippocampus
A new triple-combination drug treatment being trialled at the Mater Hospital in Brisbane could increase the life expectancy of patients with cystic fibrosis. Mater Research Institute-University of Queensland (MRI-UQ) researcher Dr. Lucy Burr said seven patients were enrolled in Phase 2 of the clinical trial, which aimed to treat the underlying cause of cystic fibrosis.
For many young children who are obese, the future might not be as grim as previously thought, a University of Michigan study suggests. According to U-M researchers, one-third of U.S. children with obesity in kindergarten achieve a lower weight status at least once through childhood, and 22 percent of these kids experience persistent remission of
Impotent men could find new hope… in an oxygen chamber Research found inhaling 100% oxygen doubles incidents of erections in men New research carried out on men with long-standing erectile dysfunction Treatment proved successful in men with no success with drug cures like Viagra Impotent men could improve their condition by having regular sessions in
Every year, Americans make 30,000 emergency room visits because of food allergies, according to the Food and Drug Administration. Even touching a surface that previously held peanuts can trigger anaphylaxis, a life-threatening allergic reaction. When a peanut-allergic person starts feeling their throat close up, they stab themselves with an epinephrine, or adrenaline, device and then