Tag: identified

A study involving scientists from the University of Alicante and the United States notes that the accumulation of a protein known as alpha-synuclein in the retina is a key Parkinson’s biomarker that could help detect the degree of severity of the disease. The work has been published this month in Movement Disorders, a journal in

The discovery of a new mechanism involved in depression – and a way to target it with a drug as effective as classical antidepressants—provides new understanding of this illness and could pave the way for treatments with fewer side effects. In a study published in Nature Medicine, a team of scientists at McGill University and

Researchers have identified a protein critical for the aggressiveness of T-cell leukemia, a subtype of leukemia that afflicts children and adults. The identification of ubiquitin-fusion degradation 1 (UFD1) allows for better understanding what causes leukemia to progress and become highly aggressive and treatment-resistant, and may lead to a new treatment for this type of cancer.

Scientists at Osaka University have discovered that Stromal derived factor-1 (SDF-1) secreted from adipocytes reduces the effectiveness of insulin in adipocytes and decreased insulin-induced glucose uptake. Insulin is a hormone that facilitates glucose uptake. Insulin binds to cellular insulin receptors to activate Insulin Receptor Substrate 1 (IRS-1), taking in sugar through phosphorylation of Akt. If

Researchers at UT Southwestern Medical Center have identified a protein that is strongly associated with metastatic breast cancer and that could be a target for future therapies. High levels of the protein ZMYND8 are correlated with poor survival in breast cancer patients, said Dr. Weibo Luo, Assistant Professor of Pathology and Pharmacology, and with the

Interruptions in workflow, such as a phone call while working on another task, or when a colleague stops by for a chat, can lead to inefficiencies in the workplace. For nurses working in emergency departments, those interruptions could affect patient care. Now, a study from the University of Missouri has determined that workflow interruptions are

Stroke and heart attack are the leading cause of death in the Western world. Würzburg scientists have used a special technique to get a clearer picture of the cells involved and their activity. Atherosclerosis is the most common cause of death and disease in the Western world. In Germany, about 300,000 people each year suffer