Tag: Intelligence

Calcium-based MRI sensor enables more sensitive brain imaging: System detects direct signals of neural activity; could reveal patterns underlying behavior

MIT neuroscientists have developed a new magnetic resonance imaging (MRI) sensor that allows them to monitor neural activity deep within the brain by tracking calcium ions. Because calcium ions are directly linked to neuronal firing — unlike the changes in blood flow detected by other types of MRI, which provide an indirect signal — this

Synaptic communication controls neuronal migration: New mechanism controls neuronal migration during brain development

The cerebral neocortex is responsible for higher brain functions, such as conscious thought and language, in humans. In the neocortex, neurons are precisely arranged in an ordered 6-layered structure. This neocortical structure is formed by the sequential generation of billions of neurons and their migration toward the brain surface in the fetal period. “Subplate neurons”

Electrode shape improves neurostimulation for small targets

A cross-like shape helps the electrodes of implantable neurostimulation devices to deliver more charge to specific areas of the nervous system, possibly prolonging device life span, says research published in March in Scientific Reports. The shape, called “fractal,” would be particularly useful for stimulating smaller areas, such as deep brain structures or the retina, since

By 2040, artificial intelligence could upend nuclear stability

A new RAND Corporation paper finds that artificial intelligence has the potential to upend the foundations of nuclear deterrence by the year 2040. While AI-controlled doomsday machines are considered unlikely, the hazards of artificial intelligence for nuclear security lie instead in its potential to encourage humans to take potentially apocalyptic risks, according to the paper.

Detecting Alzheimer’s disease before it’s too late: Intervention long before the first signs of memory issues may be required to slow disease progression

The rate at which the protein beta-amyloid accumulates into the sticky plaques associated with Alzheimer’s disease (AD) is already slowing by the time a patient would be considered to have preclinical AD, according to a longitudinal study of healthy adults published in JNeurosci. The research suggests that anti-amyloid therapies would be most effective before individuals

Blood biomarkers may allow easier detection, confirmation of concussions

Researchers from the University of California, Irvine, Georgetown University and the University of Rochester have found that specific small molecules in blood plasma may be useful in determining whether someone has sustained a mild traumatic brain injury (mTBI), commonly known as a concussion. The article, “Plasma metabolomic biomarkers accurately classify acute mild traumatic brain injury

Butterflies of the soul: Developmental origins of interneurons

Modern neuroscience, for all its complexity, can trace its roots directly to a series of pen-and-paper sketches rendered by Nobel laureate Santiago Ramón y Cajal in the late 19th and early 20th centuries. His observations and drawings exposed the previously hidden composition of the brain, revealing neuronal cell bodies and delicate projections that connect individual