A protein shredder that occurs in cell membranes of brain cells apparently also indirectly regulates the fat metabolism. This is shown by a recent study by the University of Bonn. The shredder, known as gamma-secretase, is considered a possible target for drugs against cancer and Alzheimer’s disease. However, the results suggest that such agents may
Like the cloud and the gender pay gap, metabolism is one of those things that we know exists but we don’t totally understand. Our mums, friends and random shop assistants have told us that a fast one is good and a slow one is the pits, while people constantly talk about revving it up (yeah,
The material cause of Obesity and Diabetes discovered Too much sugar and fat are unhealthy, fat and many diseases are connected, it should actually be aware of. But the question of why this is so, one inevitably comes across the question mark. What are the mechanisms in the body that we grow when we feed
In a new study researchers have found that low levels of a circulating hormone called adropin predict increased weight gain and metabolic dysregulation during consumption of a high-sugar diet in a nonhuman primate model. According to the study published in the ‘Journal of Biological Chemistry,’ these findings will help set the stage to develop new
Rats are commonly used in nonclinical pharmaceutical studies to investigate the safety, efficacy and pharmacokinetic profiles of drug candidates before they are entered into clinical studies. Most compounds administered via the oral route are metabolized in the liver and intestine, so the metabolism is a key determinant of pharmacokinetics. The uridine 5′-diphospho-glucuronosyltransferase (Ugt) superfamily is
Studies have shown that intermittent fasting can help certain people lose weight. Although researchers are still debating exactly how effective fasting can be for weight loss, new research hints at other benefits. In rats, for instance, studies show that fasting can increase lifespan. Although exciting, evidence of this in humans has yet to be seen.
How misguided saturation of the cranial nerves plunge into a crisis The global Obesity crisis today is at a record high, and rising. Research groups are desperately in search of new insights and therapeutic possibilities of intervention, in order to counteract this development. German Researchers have found a type of switch in the brain, the
Researchers have the cause of the side effects of cortisone preparations its security Cortisone is used in numerous diseases successfully, however, it often comes to unwanted side effects – among other things, in the metabolism. Why this is so, could now be investigated by an international team of researchers. Drug with a wide spectrum of
“Metabolism” is one of those buzz words that gets thrown around a lot. Effortlessly thin people, for example, are often said to be blessed with “fast metabolisms.” And, the key to weight loss is to “boost your metabolism”…right? Kind of. But that’s easier said than done, friend. First things first: What exactly is your metabolism?
Individuals with defects in copper metabolism may soon have more targeted treatment options thanks to a discovery by a research team led by Dr. Vishal Gohil of Texas A&M AgriLife Research in College Station. A paper in the Proceedings of the National Academy of Sciences reports that an investigational anticancer-drug, elesclomol, can restore the production
Sometimes it seems appropriate to amend Murphy’s Law to “Everything that can go wrong, will go wrong—and it’s probably your thyroid’s fault.” It may be small, but that butterfly-shaped gland at the base of your throat has a pretty lofty to-do list—like regulating your appetite, energy levels, and even your body temperature. When it’s working
Need another reason to love your body? It burns kilojoules all by itself – as long as you don’t get in the way. See, every cell in your body plays a role in energy metabolism – the process of turning the food you eat into energy that keeps your heart beating, lungs pumping and muscles
It’s been hard to miss the success of NBC’s “The Biggest Loser,” in which people underwent dramatic weight loss makeovers to compete for the $250,000 grand prize. But it turns out the short, grueling, extreme pace to weight loss has a price. A recent NY Times article details how Season 8 contestants have gained back
Dr. Sylvia Tara became fascinated with fat because she has always gained weight easier than everyone else. After trying several diets unsuccessfully, she wanted to understand more. Because she’s a biochemist by training, Dr. Tara had the tools to conduct her research. After several years, what she uncovered was so astounding that she decided to