04.29.18
CRISPR/Cas9 silences gene associated with high cholesterol: Technique allowed researchers to reduce blood cholesterol levels in adult mice for six months following a single treatment
Biomedical engineers at Duke University have used a CRISPR/Cas9 genetic engineering technique to turn off a gene that regulates cholesterol levels in adult mice, leading to reduced blood cholesterol levels and gene repression lasting for six months after a single treatment. This marks the first time researchers have delivered CRISPR/Cas9 repressors for targeted therapeutic gene