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Call for low-cost approach to tackle disease afflicting millions of the world’s poorest

Researchers at Brighton and Sussex Medical School (BSMS) are asking governments in the developing world to adopt a low-cost, community-based approach to prevent acute attacks that occur in patients with a devastating neglected tropical disease. A new study published in The Lancet Global Health shows that a simple package of self-care significantly reduced “acute attacks”

The cognitive-behavioural model of hoarding disorder

Standard therapy for compulsive hoarding needs to unpack many factors that contribute to the problem. This includes examining each person’s upbringing, early family history and understanding the way they think, according to Australian and US researchers. Led by Flinders University Professor Mike Kyrios, who has been conducting this research over many years while previously working

Signs of stroke in men: Early warnings and symptoms

The Centers for Disease Control and Prevention (CDC) report that strokes are the fifth-leading cause of death in the United States. They are more common and more likely to be fatal in women, while men tend to have strokes at a younger age. Being aware of all symptoms, including those specific to sex, can help

Initiative cuts overuse of tests, treatments for bronchiolitis

(HealthDay)—A multidisciplinary improvement initiative can reduce overuse of interventions for bronchiolitis, according to a study published online May 11 in Pediatrics. In an effort to reduce overuse of interventions for children with a clinical diagnosis of bronchiolitis, Amy Tyler, M.D., from the Children’s Hospital Colorado in Aurora, and colleagues used a multidisciplinary event to initiate

Why we need to figure out a theory of consciousness

Understanding the biology behind consciousness (or self-awareness) is considered by some to be the final frontier of science. And over the last decade, a fledgling community of “consciousness scientists” have gathered some interesting information about the differences between conscious and unconscious brain activity. But there remains disagreement about whether or not we have a theory

Enzyme blocker stops growth of deadly brain tumor

Investigators were able to halt the growth of glioblastoma, an aggressive form of brain cancer, by inhibiting an enzyme called CDK5, according to a Northwestern Medicine study published in Cell Reports. The discovery of this enzyme’s regulatory influence on glioblastoma may open the door to a long-awaited improvement upon current therapy options, according to Subhas

Easing the itch of poison ivy and poison oak

April showers might bring May flowers, but they also bring the arrival of troublesome plants such as poison ivy and poison oak that can cause mild to severe allergic reactions. The signature leaves of three of the poison ivy plant carry an oil called urushiol that can be an irritant if touched, broken or burned.

Study paves the way for better treatment of prostate cancer

A new study published today has found a way to identify men with locally advanced prostate cancer who are less likely to respond well to radiotherapy. Led by Professor Catharine West, The University of Manchester team created a method of selecting prostate cancer patients who would benefit from treatments which target oxygen deficient tumours. The

This Type of Exercise May Help Relieve Depression

Strength training is good for your body and your mind, according to a new review of more than 30 previously published studies. The paper, published in the journal JAMA Psychiatry, found that resistance exercise training (RET), such as weightlifting and strength training, is associated with a significant reduction in depressive symptoms. It also, of course,

New tool predicts deadly form of rare cancer

Two patients with mycosis fungoides (MF) can appear to have identical diseases upon first diagnosis but can have radically different outcomes. MF in an unusual cancer of the T lymphocyte that begins in the skin rather than in the lymph nodes, with the first sign often being a rash. Most patients with MF, the most

The joy of neurons: A simplified ‘cookbook’ for engineering brain cells to study disease

Scientists at The Scripps Research Institute have devised what they call a “neuronal cookbook” for turning skin cells into different types of neurons. As reported today in the journal Nature, the research opens the door to studying common brain conditions such as autism, schizophrenia, addiction and Alzheimer’s disease under reproducible conditions in a dish. “The