Tag: pathway

Disrupted biochemical pathway in the brain linked to bipolar disorder

Bipolar disorder affects millions of Americans, causing dramatic swings in mood and, in some people, additional effects such as memory problems. While bipolar disorder is linked to many genes, each one making small contributions to the disease, scientists don’t know just how those genes ultimately give rise to the disorder’s effects. However, in new research,

Disrupted biochemical pathway in the brain linked to bipolar disorder

Bipolar disorder affects millions of Americans, causing dramatic swings in mood and, in some people, additional effects such as memory problems. While bipolar disorder is linked to many genes, each one making small contributions to the disease, scientists don’t know just how those genes ultimately give rise to the disorder’s effects. However, in new research,

Team explores pathway to open up blood cancer treatments

Reversing runaway inflammation in the bone marrow could lead to major breakthroughs in treatments for some blood cancers, according to a new publication by scientists at Hackensack Meridian Health’s Center for Discovery and Innovation. The CDI team’s findings could ultimately improve cancer treatments for people of advanced age, like that of adult acute myeloid leukemia

Research team traces pathway to cardioprotection in post-ischemic heart failure

During an ischemic attack, the heart is temporarily robbed of its blood supply. The aftermath is devastating: reduced heart contractility, heart cell death, and heart failure. Contributing to these detrimental changes is a signaling molecule, G protein-coupled receptor kinase 2 (GRK2), which following ischemia accumulates in mitochondria, the energy-producing powerhouses of cells. Now, a Temple-led

Skin Appears to Be Key Pathway for Absorption of BBQ Fumes

FRIDAY, Aug. 3, 2018 — Dermal absorption is a more important pathway than inhalation for the intake of low-molecular-weight polycyclic aromatic hydrocarbons (PAHs) during barbecuing, according to a study published recently in Environmental Science & Technology. Jia-Yong Lao, from Jinan University in Guangzhou, China, and colleagues collected and analyzed urine samples for nine hydroxyl (OH)-PAHs