Tag: promotes

Chaperone protein imbalance promotes toxic tau buildup in the aging brain

Chaperone protein imbalance can play a significant role in initiating toxic accumulation of tau in the aging brain—an early step in the development of Alzheimer’s disease and related neurodegenerative disorders known as tauopathies, a new preclinical study by University of South Florida Health (USF Health) neuroscientists suggests. In humans, misfolding of the protein tau leads

Living macrophage-based drug promotes antitumor immunotherapy

Immunotherapy is one of the most promising approaches to inhibit tumor growth and metastasis by activating host immune functions. However, so far, immunotherapy still exhibits limitations of efficacy and safety, such as huge individual differences in treatment responses, difficulty to work on solid tumors, systemic immune storm and other immunotoxicity. Therefore, the development of advanced

Promotes Sport in the evening, sleep problems?

Evening Sport really to insomnia? Always it is recommended, before going to bed not too much effort, and being able to exercise because you sleep this bad. However, only a few weeks ago, a study was published which came to the result that in the evening sports reduces the quality of sleep. But what is

Dronedarone promotes cardiac repair after a heart attack

An article published in Experimental Biology and Medicine reports that the antiarrhythmic drug, dronedarone, promotes cardiac repair after a heart attack. The study, led by Dr. Uwe Lendeckel, Professor for Medical Biochemistry and Molecular Biology at the University Medicine Greifswald, provides mechanistic explanations for the reduced infarct size that has been observed in response to

Post-stroke delivery of neurotrophic factor MANF promotes functional recovery in rats

Stroke is the most common cause of adult disability. This is due not only to the high incidence of stroke, but also because spontaneous recovery is often incomplete and no drugs are available that hasten recovery. Mesencephalic astrocyte-derived neurotrophic factor MANF is neuroprotective when administered before experimental stroke in rats. A massive immune response mediated