Tag: regeneration

Soft tissue regeneration in a cell-free scaffold microenvironment

In a new report now published on Scientific Reports, Irini Gerges and a team of scientists in Italy and the U.S. studied the importance of biomechanical and biochemical cues to create culture conditions suited for three-dimensional (3D) regenerative microenvironments and soft tissue formation. The team observed changes in adipogenesis relative to the 3D mechanical properties

Multichannel bioreactor for lung regeneration analysis

New strides are being made toward the ex vivo growth of human lungs. In a new article published in Tissue Engineering, a peer-reviewed journal from Mary Ann Liebert, Inc., publishers, researchers report the development of a high-throughput, automated, multichannel lung bioreactor that allows parallel culture of up to five human cell-populated isolated rat lung scaffolds.

Functional regeneration of tendons using scaffolds developed via microarchitectural engineering

The underlying structure-function relationship of living tissues depends on structural and hierarchical anisotropy. Clinical exploitation of the interplay between cells and their immediate microenvironment has rarely used macroscale, three-dimensional (3-D) constructs. Biomechanical robustness is an important biomimetic factor that is compromised during biofabrication, limiting the relevance of such scaffolds in translational medicine. In a recent