Tag: research

Discovery offers novel possibilities to target drug-resistant HER2-positive cancers

SORLA is a protein trafficking receptor that has been mainly studied in neurons, but it also plays a role in cancer cells. Professor Johanna Ivaska's research group at Turku Bioscience observed that SORLA functionally contributes to the most reported therapy-resistant mechanism by which the cell-surface receptor HER3 counteracts HER2 targeting therapy in HER2-positive cancers. Removing

A NEAT reduction of complex neuronal models accelerates brain research

Neurons, the fundamental units of the brain, are complex computers by themselves. They receive input signals on a tree-like structure—the dendrite. This structure does more than simply collect the input signals: it integrates and compares them to find those special combinations that are important for the neurons’ role in the brain. Moreover, the dendrites of

Common drug colchicine brings hope to COVID fight: Canadian research

A major clinical trial in Canada shows that an inexpensive anti-inflammatory drug called colchicine can significantly reduce the risk of complications and death from COVID-19, bringing “important hope” to sufferers, the lead researcher said Sunday. Jean-Claude Tardif, head of the Montreal Heart Institute (ICM), led the study named “Colcorona,” whose preliminary results were published Friday

National research effort discovers relationship between inflammation, metabolism and scleroderma scarring

Scleroderma, a chronic and currently incurable orphan disease where tissue injury causes potentially lethal skin and lung scarring, remains poorly understood. However, the defining characteristic of systemic sclerosis, the most serious form of scleroderma, is irreversible and progressive scarring that affects the skin and internal organs. Published in iScience, Michigan Medicine’s Scleroderma Program and the

Research suggests new mechanism to balance emotional behavior

Research led by Si-Qiong June Liu, MD, Ph.D., Professor of Cell Biology and Anatomy at LSU Health New Orleans School of Medicine, discovered a surprising reciprocal interaction between chemicals in the brain resulting in accelerated loss of molecules that regulate brain cell communication. The research team’s findings are published online in Nature Communications, available here.

Research finds impacts of games psychologically complex

Florian first came to Wellington in 2014, for a trimester abroad from Göttingen University in Germany, and returned several years later to do his doctoral research. “In Germany it is rare that students can choose their own doctoral topics, so I was grateful for the chance to pursue my interest in gaming.” When he began,

Medicaid expansion not enough for diabetes patients: Study

A study led by researchers from the Boston University School of Public Health (BUSPH) claims that Medicaid expansion is not enough to improve the health care for patients with diabetes. According to a study published in the American Journal of Preventive Medicine, the Medicaid expansion which has insured improved healthcare facilities to millions of patients

Study reveals walnuts helpful in cardiovascular disease

Studies from a randomised controlled trial reveals the capability of walnuts from preventing major risk factors for heart disease, claims,’ people who regularly consume walnuts may have a lower risk of heart disease, compared to those who do not eat’. In the study, conducted by Dr Emilio Ros from the Hospital Clinic of Barcelona, in

New research supports clinical utility of circulating tumor cell count for metastatic breast cancer

Menarini Silicon Biosystems has announced the publication of a research study providing support for the reliability of using circulating tumor cell (CTC) count to guide frontline therapy choice for patients with estrogen receptor-positive (ER+), HER2-negative (HER2) metastatic breast cancer. Published in the November issue of JAMA Oncology, this is the first study to support clinical

Research team pairs 3-D bioprinting and computer modeling to examine cancer spread in blood vessels

Lawrence Livermore National Laboratory (LLNL) scientists have paired 3-D-printed, living human brain vasculature with advanced computational flow simulations to better understand tumor cell attachment to blood vessels, the first step in secondary tumor formation during cancer metastasis. The unique approach, developed with outside collaborators, lays the foundation for developing a predictive capability that can help

New research reveals the suffering of temporary migrants during the COVID-19 crisis

In the early days of the COVID-19 lockdown in March, many temporary visa holders working in heavily casualised industries, such as hospitality and retail, lost their jobs and struggled to meet basic living expenses. These included international students, backpackers, graduates, sponsored workers and refugees, among others. Despite the devastating financial impact on these temporary migrants,

Research reduces barriers for doctors treating children with autism

While autism specialists are crucial in the diagnosis and treatment of children with autism, primary care providers are very often the first to care for children with autism spectrum disorder. Two new studies reveal a range of barriers these clinicians face in recognizing and treating autism symptoms, as well as evidence that an innovative tele-mentoring