Using cells from human breast cancers and mouse breast cancer models, researchers at the Johns Hopkins Kimmel Cancer Center say they have significant new evidence that tumor cells exposed to low-oxygen conditions have an advantage when it comes to invading and surviving in the bloodstream. The experiments mapping the “fate” of the cells in two-
Mosquitoes are more likely to acquire the dengue virus when they feed on blood with low levels of iron, researchers report in the 16 September issue of Nature Microbiology. Supplementing people’s diets with iron in places where both iron deficiency anemia and dengue fever are a problem could potentially limit transmission of the disease, but
Antibiotic resistance does not spread only where and when antibiotics are used in large quantities, ETH researchers conclude from laboratory experiments. Reducing antibiotic use alone is therefore not sufficient to curtail resistance, and should be done in conjunction with measures to prevent infection with resistant germs. Bacteria are becoming increasingly resistant to common antibiotics. Often,
Breakthrough research has revealed a new drug that may prevent the spread of malaria, and also treat people suffering with the deadly parasitic disease. The findings, which were delivered by an international team of scientists led by the University of Glasgow and published today in Science, offer fresh hope in the global fight against malaria.
TUESDAY, Feb. 19, 2019 — Metastasis-free survival is significantly longer among men with nonmetastatic, castration-resistant prostate cancer treated with darolutamide versus placebo, according to a phase 3 study published online Feb. 14 in the New England Journal of Medicine to coincide with the American Society of Clinical Oncology annual Genitourinary Cancers Symposium, held from Feb.
A new study, led by the University of Chicago in Illinois, has unraveled the role of glycogen in fueling ovarian cancer spread. It is the first to reveal how tumor cells interact with support cells called cancer-associated fibroblasts to make this happen. “No systematic study,” says senior study author Ernst Lengyel, who is a professor
The urgent threat from Zika virus, which dominated news headlines in the spring and summer of 2016, has passed for now. But research into how Zika and other mosquito-borne infections spread and cause epidemics is still very active. In a paper published May 24 in the journal Cell Host & Microbe, an international team of
The Ebola outbreak in the Democratic Republic of Congo has spread to a city, the World Health Organization said Thursday, raising concern the deadly virus may prove tougher to contain. “One new case of Ebola virus disease has been confirmed in Wangata, one of the three health zones of Mbandaka, a city of nearly 1.2
The emergence of antibiotic resistance among dangerous pathogens is increasingly problematic worldwide. Many strains of infectious bacteria have become multidrug-resistant, and cannot be treated with common antibiotic therapies. While the antibiotic colistin can often be used to treat infections by multidrug-resistant bacteria, colistin resistance is also on the rise and represents an emerging global health