Scientists are batting a thousand in a project to reconstruct the mouse brain’s wiring diagram. Researchers at the Howard Hughes Medical Institute’s Janelia Research Campus have now carefully unraveled a tangle of more than 1,000 neurons, tracing each cell’s branching route across the brain to pinpoint where it goes and to which cells it connects.
The brain consists of a large collection of interconnected neurons. How complex patterns of neuronal cells grow into functioning circuits during development has fascinated researchers for decades. A team of scientists at VIB and KU Leuven has now uncovered a new signaling mechanism in fruit flies that specifies the formation of neuronal circuits in the
A team of scientists at NeuroElectronics Research Flanders (NERF- empowered by imec, KU Leuven and VIB) found that highly demanding and rewarding experiences result in stronger memories. By studying navigation in rats, the researchers traced back the mechanism behind this selective memory enhancement to so-called replay processes in the hippocampus, the memory-processing center of the
Researchers at the University of Minnesota have developed a unique 3D-printed transparent skull implant for mice that provides an opportunity to watch activity of the entire brain surface in real time. The device allows fundamental brain research that could provide new insight for human brain conditions such as concussions, Alzheimer’s and Parkinson’s disease. The research
The next time you’re offered a free sample as you’re walking past a storefront, go ahead and take it. But be aware that the more you like that little chunk of cheese or sip of herbal tea, the likelier your brain’s internal map will warp in a way that increases your ability to return to
Columbia engineers and neuroscientists have joined forces to create 3D videos of individual nerve cells moving, stretching and switching on inside fruit fly larvae as they move. Data gleaned from these videos reveals how nerve cells called proprioceptive neurons work together to help the body sense where it is in space. To accomplish this feat,
Getting enough of the omega 3 fatty acids DHA and EPA into the brain to study their effects on conditions such as Alzheimer’s and depression — which they have been shown to help — is no easy task. While supplements containing these fatty acids exist, there is scant evidence showing that these supplements actually increase
The rat in a maze may be one of the most classic research motifs in brain science, but a new innovation described in Cell Reports by an international collaboration of scientists shows just how far such experiments are still pushing the cutting edge of technology and neuroscience alike. In recent years, scientists have shown that
Research released today underscores both the dangers and the therapeutic promise of marijuana, revealing different effects across the lifespan. Marijuana exposure in the womb or during adolescence may disrupt learning and memory, damage communication between brain regions, and disturb levels of key neurotransmitters and metabolites in the brain. In Alzheimer’s disease, however, compounds found in
Contrary to popular belief, the brain is not a computer. However brains do, in their own way, compute. They integrate informational inputs to generate outputs, including behaviors, thoughts, and feelings. To process vast amounts of data, the brain uses a kind of digital code. Its cells produce discrete bursts of electric current, known as action
A study of rat brain slices published in JNeurosci demonstrates how nicotine interacts with cells that regulate the output of a brain region involved in habit formation. The research could inform efforts to help people quit smoking and avoid relapse. The addictive qualities of nicotine have been attributed to the brain’s reward system. However, recent
Dogs are capable of understanding the emotions behind an expression on a human face. For example, if a dog turns its head to the left, it could be picking up that someone is angry, fearful or happy. If there is a look of surprise on a person’s face, dogs tend to turn their head to
Activation of the immune system by an infection may temporarily disrupt formation of long-term memories in healthy, aging rats by reducing levels of a protein required for brain cells to make new connections, suggests new research published in eNeuro. Cognitive decline in old age is thought to be gradual, as in Alzheimer’s disease. However, an
In a study of mice, National Institutes of Health-funded researchers describe a new circuit involved in fine-tuning the brain’s decision either to hide or confront threats. The study, published in Nature, was partially funded by the NIH’s Brain Research through Advancing Innovative Neurotechnologies (BRAIN) Initiative. “Being able to manipulate specific circuits can uncover surprising relationships
Neuroscientists at Indiana University have reported the first evidence that non-human animals can mentally replay past events from memory. The discovery could help advance the development of new drugs to treat Alzheimer’s disease. The study, led by IU professor Jonathon Crystal, appears today in the journal Current Biology. “The reason we’re interested in animal memory
A team of researchers led by Dr. Catharine Winstanley at the University of British Columbia have uncovered a network of regions in the brain that are involved in determining the choice of working harder to get a bigger reward, or putting in a lesser effort and receiving a smaller reward. Understanding how the brain makes
Occurrence of Rift Valley Fever (RVF) has often been linked with El Niño rainfall. To curb future outbreaks of RVF, M. Kariuki Njenga and colleagues carried out enhanced syndromic surveillance of 22 high-risk RVF Kenyan counties to collect data on RVF-associated syndromes and risk factors in livestock from November 2015 through February 2016. Their research,
Evidence suggests that developing cooking and food preparation skills is important for health and nutrition, yet the practice of home cooking is declining and now rarely taught in school. A new study published in the Journal of Nutrition Education and Behavior found that developing cooking skills as a young adult may have long-term benefits for
In the early days of neuroscience research, scientists painstakingly stained brain cells and drew by hand what they saw in a microscope. Fast forward to 2018 and machines may be able to learn how to do that work. According to a new study in Cell, it may be possible to teach machines how to pick
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