Assessment of replicon ribonucleic acid COVID-19 vaccine in nonhuman primates

In a recent article posted to the bioRxiv* preprint server, researchers explored the immunogenicity of a replicon ribonucleic acid (repRNA) coronavirus disease 2019 (COVID-19) vaccine, repRNA-CoV2S, in pigtail macaques. Study: A replicon RNA vaccine induces durable protective immunity from SARS-CoV-2 in nonhuman primates after neutralizing antibodies have waned. Image Credit: nobeastsofierce/Shutterstock Background The global COVID-19 pandemic

UCHealth leaps into AR for patient engagement and experience

Photo: Nicole Caputo Patient distraction therapy, long-used by UCHealth with virtual reality and other techniques, and joy are framing the Aurora, Colorado-based health system's first in-app augmented reality experience.  Beginning this fall, a patient or visitor will be able to click a button in their UCHealth mobile app and be directed to open their device's

Study shows how microglia are prompted to change their state to adapt to different areas of the brain

From everyday actions like walking and talking to feats of athletic or academic excellence, the brain is constantly acquiring and seamlessly processing information to produce these incredible behaviors. The process requires a whole orchestra of cells listening to each other and tuning their functions to harmonize together. One of the remaining, most fundamental questions in

Can Folic Acid Halt Gastric Precancerous Conditions?

Folic acid supplementation can improve histopathologic aspects of gastric precancerous conditions (GPC), including gastric mucosal atrophy and intestinal metaplasia, according to results of a meta-analysis of relevant research. The results, say the authors, provide evidence for the potential clinical use of folic acid in the management of GPC. “We believe doctors can try to use

‘Shocking’ and Persistent Gap in Treatment for Opioid Addiction

The vast majority of Americans with opioid use disorder (OUD) do not receive potentially lifesaving medications. Drugs such as methadone, buprenorphine, and extended-release naltrexone have been shown to reduce opioid overdoses by more than 50%. Yet a new analysis shows that only about 1 in 10 people living with OUD receive these medications. Dr Noa

How to Talk To Relatives That Don't 'Get' Your Mental Health Needs

We can all agree that mental health is important. One of the most positive and healthiest signs of our current culture is how much more open and accepting we are about discussing mental health needs, including seeking therapy, establishing boundaries, and what it’s like to experience anxiety and depression. This receptivity to mental health can