A commonly available oral diuretic pill approved by the U.S. Food and Drug Administration may be a potential candidate for an Alzheimer’s disease treatment for those who are at genetic risk, according to findings published in Nature Aging. The research included analysis showing that those who took bumetanide—a commonly used and potent diuretic—had a significantly lower
What makes one person drive above the speed limit while another navigates steadily in the right lane? What motivates someone to leave a job with a steady paycheck to launch their own business while the other sticks to one employer for an entire career? “People have different tendencies to engage in behavior that risks their
Adagio Therapeutics today published in vitro and in vivo data in Science on its lead antibody candidate, ADG2, which demonstrated similar or higher potency against SARS-CoV-2 compared to other monoclonal antibodies (mAbs) in clinical development and strong binding to all known SARS-CoV-2 variants. Uniquely, ADG2 also showed broad and potent neutralization against a range of
Across the US, states are increasingly using preemption to stymie local advancement of public health policy strategies, according to updated data released today to LawAtlas.org by the Center for Public Health Law Research and the National League of Cities with support from the Robert Wood Johnson Foundation. The updated data capture state preemption of local
Documents released by U.S. regulators Tuesday confirmed that Pfizer’s vaccine was strongly protective against COVID-19 and appeared safe—offering the world’s first detailed look at the evidence behind the shots. The positive review from the Food and Drug Administration sets the stage for a decision allowing the vaccine’s initial use within days. FDA regulators posted their
Research scientists from Regenstrief Institute and Indiana University have further improved the performance of Uppstroms, a machine learning application that identifies patients who may need referrals to wraparound services, by incorporating additional personal and population-level data sources and advanced analytical approaches. Research team affiliations include Regenstrief, IU Fairbanks School of Public Health at IUPUI, IU
A COVID-19 vaccine candidate that underwent extensive preclinical testing at the University of Alabama at Birmingham this spring and summer shows potent preclinical immune responses—including several that distinguish it from other COVID-19 vaccine approaches—according to a preprint deposited in the BioRxiv repository this week. Partial preclinical results had been announced in July and August by
Nine months after the coronavirus emerged, there’s still a remarkable lack of understanding about why the severity and course of COVID-19 vary for different people. Part of the problem is that we haven’t prioritized gathering and reporting data in enough detail. Most countries just report the age and sex of people who have died of
The MINDtick app was developed in South Australia by Flinders University and mental health technology developer goAct to assist with the early and accurate diagnosis and management of mental illness by allowing access to a person’s smartphone data. The app draws on mobile phone data, such as information about a user’s location, to see how
The increased use of medical helicopters over the last half-century has saved countless lives by quickly getting patients from trauma to the emergency room (ER) within the so-called “golden hour.” But a growing number of medical experts contend emergency helicopters may be overused in some transfer situations. Their concern: Patients stuck with an exorbitant cost
In 1906, English statistician Francis Galton happened to visit a livestock fair where fairgoers were invited to guess the dressed weight of an ox scheduled for imminent slaughter. Some 800 attendees took part and afterwards Galton got hold of the contest data. This episode, which Galton reported in Nature, has become subject to popular retellings,
A research team based at Tokyo Medical and Dental University (TMDU) has used an integrated data analysis to classify hepatocellular carcinoma, the most common type of liver cancer, into three distinct subgroups, which should aid targeted treatment Liver cancer remains a major problem in healthcare globally, being the second most common cause of cancer-related death
(HealthDay)—An analysis of electronic health record data reveals considerable differences in hypertension control across health systems, according to a study published in the November-December issue of the Journal of the American Board of Family Medicine. Kevin Selby, M.D., from the Kaiser Permanente Division of Research in Oakland, California, and colleagues conducted a retrospective cohort study
In the last few years, cloud computing has moved from an option for healthcare providers to, increasingly, a business necessity. By outsourcing data management to a cloud services company, hospitals can free up their own technical staff to do more work closer to their core competencies. “Microsoft coming along with a public cloud infrastructure, once
(HealthDay)—Pediatric exposure to buprenorphine can result in serious adverse outcomes, especially among children aged younger than 6 years, according to a study published online June 25 in Pediatrics. Sara Post, from The Research Institute at Nationwide Children’s Hospital in Columbus, Ohio, and colleagues examined buprenorphine exposures among children and adolescents aged ≤19 years in the
EMBL researchers have designed a computational method to jointly analyse multiple types of molecular data from patients in order to identify molecular signatures that distinguish individuals. The method is called Multi-Omics Factor Analysis (MOFA), and was published in Molecular Systems Biology today. MOFA could be particularly useful for understanding cancer development, improving diagnosis and suggesting
(HealthDay)—Data breaches affecting health care systems or their partners need to be addressed quickly, according to an article published in Medical Economics. Noting that every successful breach against a health care system constitutes a Health Insurance Portability and Accountability Act violation, which must be reported, the authors discuss the importance of keeping an eye on
New research on Google trends data presented at this year’s European Congress on Obesity in Vienna, Austria (23-26 May) shows that over time, searches using the terms weight loss have increased, while those using the word obesity have decreased, potentially suggesting a normalisation of obesity in society. The study is by Dr. Aditya S. Pawar
To the beat of electronic dance music, men and women inside a slate-gray building harvested marijuana plants festooned with radio-frequency identification tags. In another room, an employee entered the tag numbers into a government database. The cannabis tracking system used by Avitas, a marijuana company with a production facility in Salem, is the backbone of
Google is likely to be scrutinized next, as it harvests user data at a bigger scale than Facebook. The Facebook privacy breach rattled users all around the globe, but some believe the problems are just beginning. For instance, Google reportedly collects so much data on each person, that if it were all printed, it would
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