Tag: Researchers

Researchers at Oregon State University and Oregon Health & Science University have found a possible counterpunch to the drug resistance of melanoma, the most dangerous form of skin cancer. The findings, published today in the journal Molecular Carcinogenesis, are important because in the United States alone, almost 100,000 new melanoma cases will be diagnosed this

A team of WA researchers has uncovered new genes that could play an important role in the development of sarcoma, a group of rare bone, muscle and connective tissue cancers. The study, undertaken by Ph.D. student Rachel Jones and led by Associate Professor Evan Ingley from the Harry Perkins Institute of Medical Research and Murdoch

Scientists at VCU Massey Cancer Center have identified key biological pathways that regulate the spread of tumor cells to vital organs. These findings may have a significant influence on the development of new therapies that slow or prevent breast cancer metastasis. Metastasis refers to the spread of cancer cells to other organs, and the likelihood

A team of researchers from Clemson University and Prisma Health-Upstate are working to create a screening process to catch ovarian cancer in the early or pre-cancerous stages. Their goal is to make this screening as simple and easy for women as getting a pap smear. The idea is to identify the pre-cancerous changes through the

Researchers in New York have found that treating human prostate cancer cells with a drug that targets a protein called PHLPP2 may prevent the cancer cells from spreading to other organs in the body. The study, which will be published May 15 in the Journal of Cell Biology, reveals that inhibiting PHLPP2 lowered the levels

University of Toronto researchers used a novel data-mining approach to uncover the most common medical problems affecting people in the time before they suffered a traumatic brain injury (TBI). The results can be used to better predict and prevent these life-altering incidents. Professor Michael Escobar, a biostatistician at the Dalla Lana School of Public Health,

A team of Florida State University researchers used a simple tumor model to show the importance of tissue microenvironment in primary tumor formation. In the journal Developmental Cell, FSU researchers explain how certain signaling pathways define tumor hotspots, tissue microenvironment favorable for tumorigenesis, and show that simple stimulation of a protein can lead directly to

New research has found it is not just what you eat, but when you eat that is important, knowledge which could improve the health of shift workers and people suffering from jet lag. The Medical Research Council (MRC)-funded study, published today in the journal Cell, is the first to identify insulin as a primary signal

If a patient is treated for ischemic stroke after-effects using the cerebral hypothermia method, their diet is adjusted, and they are expected to consume 20-25 Kcal per 1 kilogram of body weight. RUDN researchers demonstrated that this value should be reduced by 15-20% to decrease the mortality and disability rate among such patients by half.

A virtual reality therapy game (iVRT) which could provide relief for patients suffering from chronic pain and mobility issues has been developed by a team of UK researchers. Dr. Andrew Wilson and colleagues from Birmingham City University built the CRPS app in collaboration with clinical staff at Sandwell and West Birmingham Hospitals NHS Trust for

Researchers have identified a biomarker and a possible new therapy for melanoma. Microphthalmia-associated transcription factor (MITF) is a protein that plays a pivotal role in the maintenance of the melanocyte (cells that make melanin) lineage, differentiation of normal and malignant melanocytes and the survival of melanoma cells. “We have now detected the first useful chemical

Our brains are incredibly good at processing faces, and even have specific regions specialized for this function. But what face dimensions are we observing? Do we observe general properties first, then look at the details? Or are dimensions such as gender or other identity details decoded interdependently? In a study published in Nature Communications, neuroscientists

A new method of determining the sequence of molecules in DNA can be used to detect small fragments of cancerous genetic material in blood samples from lung cancer patients with a high degree of accuracy, according to new research published in the leading cancer journal Annals of Oncology today. Results from analyses of so-called “liquid

Researchers at the San Diego branch of the Ludwig Institute for Cancer Research at University of California San Diego, with colleagues around the country, report that inhibiting activity of a specific protein in glioblastomas (GBM) boosts their sensitivity to radiation, thus improving treatment prospects for one of the most common and aggressive forms of brain

Understanding and mitigating the role of epigenetics (environmental influences that trigger changes in gene expression) in disease development is a major goal of researchers. Now, a newly published paper featured on the March cover of the journal Brain adds significantly to this work by detailing how metabolites can be used to inhibit epigenetic mechanisms and

A team of researchers affiliated with several institutions in the U.S. and one in the U.K. has found that blocking a certain inflammatory pathway in mice protects tendons from injury. In their paper published in the journal Science Translational Medicine, the group describes their study of tendinopathies and possible ways to prevent them. Most people

It was the diet du jour of the noughties, as popularised by the Paleo diet, the broscience diet, Atkins v2.0 and the Dukan diet. Carbs were out of fashion so we needed something to replace them with. Besides, high protein diets left people feeling full for longer and, some studies showed, they led to greater

How are the images cast on the retina reassembled in the brain? Researchers in Munich and Tuebingen find that processing of visual stimuli occurs at the earliest waystation on the way to the visual cortex—but not all inputs are treated equally. In humans, the visual system collects up to 80 percent of all the sensory

Decades of research into anxiety and depression have resulted in the development of models that help explain the causes and dimensions of the two disorders. For all of their well-established utility however, these models measure differences between individuals and are derived from studies designed using few assessments that can be months or even years apart.

Love can make us do crazy things. It often prompts us to behave in counterintuitive ways, like, for example, placing the wellbeing of our loved ones above our own. But why? Such altruism has perplexed and intrigued scientists for centuries. A new study out of UC Santa Barbara explores how an individual’s genetics and brain