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Study suggests most humans are vulnerable to type 2 diabetes

Scientists have found that insulin has met an evolutionary cul-de-sac, limiting its ability to adapt to obesity and thereby rendering most people vulnerable to Type 2 diabetes. A recent study from scientists at Indiana University School of Medicine, the University of Michigan and Case Western Reserve University has determined that the sequence of insulin has

What It Feels Like… to have incurable cancer

Most people born in the UK today can expect to live until they’re about 80. Having been diagnosed with incurable breast cancer some 18 months ago, aged just 55, I’ll be lucky to make it to my 60s. How do I deal with that knowledge? I find ways, otherwise I would go mad worrying about

Helping the immune system to combat cancer

Cancers sometimes escape our immune defenses because of the over-activity of molecular signaling systems, called checkpoint processes. Now we may be able to fight back using a new range of molecules, researchers in China report in the European Journal of Medicinal Chemistry. “We have been working on the discovery of anti-cancer agents for more than

Could SARS-CoV-2 evolve resistance to COVID-19 vaccines?

Similar to bacteria evolving resistance to antibiotics, viruses can evolve resistance to vaccines, and the evolution of SARS-CoV-2 could undermine the effectiveness of vaccines that are currently under development, according to a paper published November 9 in the open-access journal PLOS Biology by David Kennedy and Andrew Read from Pennsylvania State University, U.S. The authors

Curbing COVID-19 hospitalizations requires attention to construction workers

Construction workers have a much higher risk of becoming hospitalized with the novel coronavirus than non-construction workers, according to a new study from researchers with The University of Texas at Austin COVID-19 Modeling Consortium. Analyzing data from mid-March to mid-August on hospitalizations in Austin, Texas, the researchers found that construction workers there were five times

Study helps explain why motivation to learn declines with age

As people age, they often lose their motivation to learn new things or engage in everyday activities. In a study of mice, MIT neuroscientists have now identified a brain circuit that is critical for maintaining this kind of motivation. This circuit is particularly important for learning to make decisions that require evaluating the cost and

Cancer’s dangerous renovations to our chromosomes revealed

Cancer remodels the architecture of our chromosomes so the disease can take hold and spread, University of Virginia researchers have revealed. This remodeling is important because the arrangement of the components in our chromosomes actually affects the workings of our genes. With these renovations, cancer begins making a comfortable home for itself inside our cells.

Most Americans want to end seasonal time changes: survey

(HealthDay)—As most of America prepares for the Nov. 1 return of standard time, 63% want one fixed, year-round time, a new survey finds. “Evidence of the negative impacts of seasonal time changes continue to accumulate, and there is real momentum behind the push to end seasonal time changes,” said Dr. Kannan Ramar, president of the

Q&A: Getting to the roots of fragile X syndrome

The cause of fragile X syndrome (FXS), the most common inherited intellectual disability, is easy to see in the lab. Under electron microscopy, an affected X chromosome exhibits a deformed tip that gives the disorder its name and pinpoints the causative gene malfunction. There’s no cure for the disease, whose symptoms include learning deficits and

Time to Diagnosis Longer for Subtle Seizures in Focal Epilepsy

TUESDAY, Oct. 20, 2020 — Patients with new-onset focal epilepsy with subtle seizures experience prolonged time to diagnosis, according to a study published online Oct. 20 in Epilepsia. Jacob Pellinen, M.D., from the New York University School of Medicine in New York City, and colleagues examined the causes and consequences of delayed diagnosis in patients

Estée Lauder hosts live stream for women to check their breasts

Have you checked your breasts for lumps lately? Some people feel uncomfortable with the idea of giving their boobs a squeeze for fear of what they might find or because they are worried about doing it wrong. Well, ladies (but also gents), it’s time. For Breast Cancer Awareness Month, Estée Lauder is hosting a global breast-check, open