Approximately 8.3 million adults in the United States reported thinking about suicide last year, according to the Centers for Disease Control and Prevention. While thoughts and deeds are clearly different, University of Houston professor of psychology Rheeda Walker has examined both and finds that current approaches to suicide prevention are troubling, because they usually consist
Rats are commonly used in nonclinical pharmaceutical studies to investigate the safety, efficacy and pharmacokinetic profiles of drug candidates before they are entered into clinical studies. Most compounds administered via the oral route are metabolized in the liver and intestine, so the metabolism is a key determinant of pharmacokinetics. The uridine 5′-diphospho-glucuronosyltransferase (Ugt) superfamily is
Researchers from Washington State University have discovered how a genetic mutation linked to hypertrophic cardiomyopathy (HCM) disrupts the heart’s normal function. The study, which will be published May 18 in the Journal of General Physiology, reveals that the mutation prevents the heart from increasing the amount of force it produces when it needs to pump
(HealthDay)—The overall rate of heart disease in the United States has declined 38 percent since 1990, a new report shows. Not every state has benefited equally, however. Between 2010 and 2016, 12 states actually saw their heart disease rates begin to creep up again, the data showed. And although the United States as a whole
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