Tag: Addiction

Nicotine alters neurotransmission in habit-forming brain region: Nicotine reduces dorsal striatal output, which may underlie urge to smoke and make it difficult to break the habit

A study of rat brain slices published in JNeurosci demonstrates how nicotine interacts with cells that regulate the output of a brain region involved in habit formation. The research could inform efforts to help people quit smoking and avoid relapse. The addictive qualities of nicotine have been attributed to the brain’s reward system. However, recent

Adolescent binge drinking disrupts mouse memory in adulthood: Study could help scientists better understand development of alcohol use disorders in adults

Excessive drinking during adolescence may interfere with the activity of brain cells needed for sustaining short term memory, according to new research in adolescent male mice published in JNeurosci. The study could help scientists better understand the development of alcohol use disorders in adults. The prefrontal cortex (PFC) and the behavior-management abilities it supports —

In the addiction battle, is forced rehab the solution?

The last thing Lizabeth Loud, a month from giving birth, wanted was to be forced into treatment for her heroin and prescription painkiller addiction. But her mother saw no other choice, and sought a judge’s order to have her committed against her will. Three years later, Loud said her month in state prison, where Massachusetts

Magnetic stimulation dampens brain response to drug cues in addiction

In a study investigating the use of transcranial magnetic stimulation (TMS) for drug addiction, researchers at Medical University of South Carolina are the first to demonstrate that the noninvasive brain stimulation technique can dampen brain activity in response to drug cues in chronic alcohol users and chronic cocaine users. The findings are published in Biological

Prescription drug monitoring programs may have negative unintended consequences: Study shows programs may be linked to fatal drug overdoses

Prescription drug monitoring programs (PDMPs) are a key component of the President’s Prescription Drug Abuse Prevention Plan and considered a critical tool for reducing prescription opioid-related illness and death. The results of a study just conducted at Columbia University’s Mailman School of Public Health and University of California, Davis, show there is insufficient evidence to

Revisiting existing drugs finds molecules that control body clocks: Discovery of an anti-aging supplement that reduces jet lag in mice

Using drug repurposing, a team of researchers led by animal biologists at Nagoya University has discovered compounds that can either shorten or lengthen the circadian rhythm in human cells. A hormone, also known as a common anti-aging supplement demonstrated period-shortening activities, and when it was fed to mice, jet lag symptoms were significantly reduced. Further