Scientists develop breakthrough technology for detecting protein modifications

Reviewers’ Notes A team of scientists led by the University of Oxford have achieved a significant breakthrough in detecting modifications on protein structures. The method, published in Nature Nanotechnology, employs innovative nanopore technology to identify structural variations at the single-molecule level, even deep within long protein chains. Human cells contain approximately 20,000 protein-encoding genes. However,

Two 30 minute exercises that could help slash bad cholesterol

High cholesterol: Nutritionist reveals top prevention tips Having high cholesterol means you have too much of a fatty substance known as cholesterol in your blood. Over time this can lead to blockages in your blood vessels, causing serious damage. Although it can sometimes run in families, having high cholesterol is typically associated with unhealthy lifestyle

Jab of gel that could help prolong men's love-making

This jab of gel could help prolong men’s love-making The Arab Journal of Urology reports that the jabs were still effective a year later  Jabs made with a gel found in eye drops have been used to treat premature ejaculation. Volunteers given injections of the jelly-like substance, hyaluronic acid, had an eight-fold increase in ejaculation

Trial evaluates purine P2X7 receptor antagonist JNJ-54175446 in patients with major depressive disorder

In a recent study published in Translational Psychiatry, researchers investigated the safety and pharmacokinetics of JNJ-54175446 in a double-blind, multicenter, randomized controlled trial (RCT) in the Netherlands and Germany. Study: Characterization of the central nervous system penetrant and selective purine P2X7 receptor antagonist JNJ-54175446 in patients with major depressive disorder. Image Credit: fizkes/Shutterstock.com The study population

Why I've signed up for the UK's largest medical study

ETHAN ENNALS: Why I’ve signed up for the UK’s largest medical study to help firefighters such as Kieran and Miriam’s grandchildren Five million volunteers have been tasked with taking part in a £270m study, The test will track one in ten Britons for the entire length of their lives   Latest Wimbledon 2023 news, including schedule,

Novel noninvasive test for malaria does not require a blood sample

Reviewers’ Notes A novel testing platform under development by researchers at the Yale School of Public Health (YSPH) and CytoAstra, LLC could provide a new noninvasive test for malaria that doesn't require a blood sample. The platform technology, known as cytophone, detects malaria infection in blood cells using lasers and ultrasound. Researchers developing the platform

From bench to bedside: A promising option for unremitting ulcerative colitis

Many existing treatments for inflammatory bowel disease, like Remicade and Humira, work by blocking inflammatory cytokines such as tumor necrosis factor (TNF) and interleukins IL-12 and IL-23, which are over-produced in autoimmune disease. But few patients with ulcerative colitis get complete relief from these drugs. A small but promising open-label clinical trial, published recently in