New Dialysis Technique Boosts Survival in Kidney Failure

High-dose hemodiafiltration (HDF) produced substantially better survival compared with conventional, high-flux hemodialysis in people with end-stage kidney disease (ESKD) in CONVINCE, a randomized, multicenter trial of 1360 patients treated for a median of 30 months. The results show that high-dose HDF, with a convection volume of greater than 23 L/session, improved overall survival by 23%

Diagnosis of rare, genetic muscle disease improved by new approach

It’s not easy to distinguish between the dozens of subtypes of limb girdle muscular dystrophy—a rare, genetic muscle disease characterized by weakness in the hips and shoulders that causes difficulty walking and lifting the arms. Until now, determining the subtype has not been critical in caring for patients, because no specific treatments have been available.

Breastfeeding can protect mothers against type 2 diabetes in later years

Breastfeeding can improve the number of insulin-producing cells in the pancreas and increase insulin sensitivity in mothers, helping to protect them against type 2 diabetes in later years, suggests a mice study presented Thursday at ENDO 2023, the Endocrine Society's annual meeting in Chicago, Ill. Many previous studies in women have shown that prolonged breastfeeding

Scientists discover spiral-shaped signals that organize brain activity

University of Sydney and Fudan University scientists have discovered human brain signals traveling across the outer layer of neural tissue that naturally arrange themselves to resemble swirling spirals. The research, published today in Nature Human Behaviour, indicates these ubiquitous spirals, which are brain signals observed on the cortex during both resting and cognitive states, help

A Promising New Approach to Treating Chronic Diabetic Foot

A new platelet-rich fibrin (PRF) matrix is becoming a promising and affordable alternative for treating chronic diabetic ulcers (diabetic foot), a pilot study conducted in São Paulo, Brazil, suggests. The authors used a third-generation PRF (Progressive PRF or PRO-PRF) created by researchers from the Federal University of Juiz de Fora (UFJF). PRF is a concentrate obtained

Phase 3 clinical trial shows favorable safety and immunogenicity profile of single-shot live-attenuated chikungunya vaccine

In this review published in The Lancet, researchers performed a double-blinded, phase III randomized trial to gather safety and immunogenicity data for a live-attenuated vaccine (LAV) candidate 'VLA1553' for the chikungunya virus. They reported data up to day 180 post-vaccination for 4,115 healthy participants. Study: Safety and immunogenicity of a single-shot live-attenuated chikungunya vaccine: a double-blind,

‘Professional Grief’ Is a Daily Reality for Oncologists

Oncologists commonly suffer “professional grief” when a patient dies — in fact, it is a “familiar, daily reality for the oncology clinician,” says one — but when it is also accompanied by a sense of emotional isolation, it can lead to reduced well-being and burnout. The issue was discussed at a special session at the

Molecular insights into long COVID: serum proteome reveals dominant signaling pathways

In a recent study published in the Nature Communications Journal, researchers examined the serum proteome of unvaccinated adults who had post-acute sequelae of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) (PASC) and were infected with the SARS-CoV-2 ancestral strain. Study: Persistent serum protein signatures define an inflammatory subcategory of long COVID. Image Credit: DmitryDemidovich/Shutterstock.com Background Long coronavirus

‘Smart’ drugs can decrease productivity in people who don’t have ADHD, study finds

New research from the University of Cambridge and the University of Melbourne, published in Science Advances, shows neurotypical workers and students taking cognitive enhancers, or “smart” drugs, may actually be inhibiting their performance and productivity. Drugs such as methylphenidate, sold under the brand name Ritalin among others, are commonly prescribed for attention deficit hyperactivity disorder

19 Sweet & Savory Ways to Use Up Your Fresh Summer Berries

If you purchase an independently reviewed product or service through a link on our website, SheKnows may receive an affiliate commission. The minute summer begins, berry season is already in full swing. Take blueberries and strawberries, for instance: The former kicks off in May and extends into early October, while strawberries are harvested as early