Long-COVID risk reduced with Omicron versus Delta

In a recent study published in The Lancet, researchers at King's College London and ZOE Limited assessed the risk of long coronavirus disease (COVID) associated with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Delta and Omicron variants in the United Kingdom (UK). Studies have reported that Omicron causes acute SARS-CoV-2 infections of lesser severity compared

Multifunctional nanoparticle system may be a promising therapeutic way for breast cancer therapy

In this new article publication from Acta Pharmaceutica Sinica B, authors Yun Yang, Danrong Hu, Yi Lu, Bingyang Chu, Xinlong He, Yu Chen, Yao Xiao, Chengli Yang, Kai Zhou, Liping Yuan and Zhiyong Qian from Sichuan University, Chengdu discuss tumor-targeted/reduction-triggered composite multifunctional nanoparticles for breast cancer chemo-photothermal combinational therapy. Breast cancer has become the most

Zanubrutinib-Obinutuzumab Doubles PFS in Follicular Lymphoma

For patients with follicular lymphoma, adding zanubrutinib to obinutuzumab more than doubled progression-free survival (PFS) compared with use of obinutuzumab alone, new phase 2 research shows. Overall, the combination therapy was associated with a 49% lower risk of progression or death compared with obinutuzumab, according to lead investigator Pier Luigi Zinzani, MD, of the Institute

FDA authorizes 1st COVID-19 shots for infants, preschoolers

U.S. regulators on Friday authorized the first COVID-19 shots for infants and preschoolers, paving the way for vaccinations to begin next week. The Food and Drug Administration’s action follows its advisory panel’s unanimous recommendation for the shots from Moderna and Pfizer. That means U.S. kids under 5—roughly 18 million youngsters—are eligible for the shots, about

FDA Approves Setmelanotide for Obesity in Bardet-Biedl Syndrome

The US Food and Drug Administration (FDA) has approved a supplemental indication for setmelanotide (Imcivree, Rhythm Pharmaceuticals) injection for chronic weight management in adults and pediatric patients age 6 and older with obesity due to Bardet-Biedl Syndrome (BBS). Setmelanotide, a melanocortin-4 receptor (MC4R) agonist, is the first FDA-approved therapy for BBS, a rare genetic disorder

Lower-Dose Antipsychotics Benefit Patients with Schizophrenia

NEW ORLEANS — Patients with treatment-refractory schizophrenia in a long-term forensic facility showed significant stabilization following reduced doses of long-acting injectable antipsychotics, a study revealed. Dr Mujeeb Shad “There is an argument by some experts in the field that state hospital populations represent a different set of patients who require higher antipsychotic dosages, with no alternative,

New pediatric obesity program makes treatment more accessible

Pediatric obesity remains a serious health problem in the United States, where one in five children are affected. The U.S. Preventive Services Task Force now recommends that pediatricians screen for obesity during primary care visits and refer families to behavioral intervention programs. While there is growing interest in providing these services, accessibility continues to challenge

Glucose meter can detect SARS-CoV-2 antibodies in patient samples

Over-the-counter COVID tests can quickly show whether you are infected with SARS-CoV-2. But if you have a positive result, there's no equivalent at-home test to assess how long you're protected against reinfection. In the Journal of the American Chemical Society, researchers now report a simple, accurate glucose-meter-based test incorporating a novel fusion protein. The researchers