(HealthDay)—For patients with breast cancer, endocrine therapy-induced alopecia (EIA) has a pattern that is similar to androgenetic alopecia, according to a study published online April 11 in JAMA Dermatology. Azael Freites-Martinez, M.D., from the Memorial Sloan Kettering Cancer Center in New York City, and colleagues conducted a retrospective cohort study to characterize EIA in 112
A Purdue University-patented technology shows promise in using microscopic bubbles filled with oxygen to help with various medical treatments, including improving cancer therapeutics and helping wounds heal faster. Samara Biotech LLC, a Purdue startup, has developed an easy-to-use method to inject oxygen “nanobubbles” intravenously so they can be targeted precisely at wounds or cancerous tumors.
A large register-based study conducted in Sweden has found that statins are associated with a markedly reduced risk of all-cause mortality, liver transplantation, liver cancer, and variceal bleeding in patients with primary sclerosing cholangitis (PSC). The study, which reviewed the records of almost 3,000 patients diagnosed with PSC between 2005 and 2016, also reported a
Surveillance for hepatocellular carcinoma (HCC) by ultrasound is likely to be cost effective in patients with hepatitis C-related liver cirrhosis after they have achieved a sustained virological response (SVR) to direct-acting antiviral agents (DAAs), according to the results of a Canadian study presented today. The study also found that screening is very unlikely to be
With springtime comes the desire to shed those few extra pounds, in preparation to don swimsuits and head to the pool. This year, new obesity research is making it easier to find a pathway that is right for us. There is no doubt that weight loss is a higher priority than ever before. Americans have
Researchers at the University of Michigan Life Sciences Institute and the Howard Hughes Medical Institute have determined how satellite DNA, considered to be “junk DNA,” plays a crucial role in holding the genome together. Their findings, published recently in the journal eLife, indicate that this genetic “junk” performs the vital function of ensuring that chromosomes
Melanoma, a relatively rare but deadly skin cancer, has been shown to switch differentiation states—that is, to regress to an earlier stage of development—which can lead it to become resistant to treatment. Now, UCLA researchers have found that melanomas can be divided into four distinct subtypes according to their stages of differentiation. Cell subtypes that
For many people, one of the unspoken rules for being cool is maintaining an emotionally inexpressive attitude. This message is reinforced through advertisements where fashion models rarely smile and by quotes from celebrities. In an article in the Huffington Post, Kanye West said he doesn’t smile in photographs because “it just wouldn’t look as cool.”
For many people, one of the unspoken rules for being cool is maintaining an emotionally inexpressive attitude. This message is reinforced through advertisements where fashion models rarely smile and by quotes from celebrities. In an article in the Huffington Post, Kanye West said he doesn’t smile in photographs because “it just wouldn’t look as cool.”
Immunotherapies are treatments that stimulate a patient’s immune cells to attack tumors. They can be very effective in melanoma—a common and aggressive form of skin tumor—but nonetheless fail in the majority of patients. To address this, researchers are trying to identify the factors that enable successful immunotherapy, as well as those that may limit it.
Because testicular cancer has a 95 percent cure rate, it is easier for men to move on and forget about it. But new research in the Journal of Clinical Oncology shows that it’s prudent for patients to stay in touch with their medical team as they age and to be aware of treatment toxicities. The
Thinking of trying that trendy diet your friends raved about on Instagram? Before you’re ready to declare the latest celebrity fad the best diet plan, check the science first. While many diets promise quick weight loss, they often have a downside. We asked two USC experts to help us separate truth from hype for four
Two common iron compounds increase the formation of a known biomarker for cancer, according to a new study of cancer cells from Chalmers University of Technology, Sweden. The two compounds, ferric citrate and ferric EDTA, are often used in dietary supplements and as a food additive respectively, in worldwide markets including the U.S. and the
The emergence of antibiotic resistance among dangerous pathogens is increasingly problematic worldwide. Many strains of infectious bacteria have become multidrug-resistant, and cannot be treated with common antibiotic therapies. While the antibiotic colistin can often be used to treat infections by multidrug-resistant bacteria, colistin resistance is also on the rise and represents an emerging global health
Further evidence that immunotherapy provides long-term survival benefit for patients with lung cancer was presented today at ELCC 2018 (European Lung Cancer Congress) in Geneva, Switzerland. Researchers presented the three-year survival results of the randomised phase 2 POPLAR trial in second line, which is the longest follow-up reported to date with anti-programmed death ligand 1
Geisinger Health System CEO David Fineberg, MD, and other top executives said Geisinger’s gene sequencing program is helping to better project adverse health issues in the short-term and the hospital is expecting even better results to come. Geisinger’s DNA sequencing project has the potential to identify virtually everyone in its patient population to pinpoint increased
(HealthDay)—The overall rate of heart disease in the United States has declined 38 percent since 1990, a new report shows. Not every state has benefited equally, however. Between 2010 and 2016, 12 states actually saw their heart disease rates begin to creep up again, the data showed. And although the United States as a whole
Researchers at the University of Cincinnati (UC) College of Medicine have found that a newly identified subset of a known genetic variant found primarily in individuals of South Asian descent may be a better marker for carriers of heart dysfunction in this population and that individuals with this genetic variant are more likely to develop
Vertebrate species, including humans, exposed to stress prenatally tend to have higher stress hormones after birth, according to a new Dartmouth-led study published in Scientific Reports. While previous research has reported examples of maternal stress experience predicting offspring stress hormones in different species, this study is the first to empirically demonstrate the impact of prenatal
Researchers from Mount Sinai and Sema4, a health information company and Mount Sinai venture, have discovered that giving metastatic bladder cancer patients simultaneous chemotherapy and immunotherapy is safe and that patients whose tumors have certain genetic mutations may respond particularly well to this combination approach, according to the results of a clinical trial published in
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