A multi-institutional research team has identified what may be a novel mechanism underlying acquired resistance to CDK 4/6 inhibitor treatment for breast cancer. In their report published in the Annals of Oncology, the team—led by investigators at Massachusetts General Hospital (MGH), Institute Gustave Roussy in Paris, and Texas Oncology-Baylor Sammons Cancer Center/U.S. Oncology in Dallas—reports
For the first time, scientists have deconstructed the brain circuits that orchestrate parenting behavior in mice. The team, led by Howard Hughes Medical Institute Investigator Catherine Dulac, has discovered that more than 20 different parts of the brain are integrated into this circuitry. Distinct sets of cells within a parenting-control hub trigger the motivational, behavioral,
A new study shows that more frequent and severe menopausal symptoms such as hot flashes, sleep disturbance, loss of sexual interest, weight gain and other quality of life measures, were associated with markers of vascular aging, according to researchers at the University of Colorado Anschutz Medical Campus. The researchers, however, found no association between these
The class of drugs currently prescribed to treat male erectile dysfunction has been flagged for its potential to be included in new trials for anti-cancer drugs, in a new clinical study published today in the open access journal, ecancermedicalscience. The paper is the latest publication from the Repurposing Drugs in Oncology (ReDO) project, an international
New research on bowel cancer has shown that every tumour is different, and that every cell within the tumour is also genetically unique. In the first study of its kind, researchers from the Wellcome Sanger Institute, UK and Hubrecht Institute (KNAW) in Utrecht, The Netherlands, used the latest single cell and organoid technologies to understand
Professor Sir Ian Wilmut – who led the team that created Dolly the sheep – has backed an initiative to tackle Parkinson’s disease, after being diagnosed with the condition. The eminent scientist announced his diagnosis today – World Parkinson’s Day – ahead of the launch of a major research programme that will see experts at
An American, a Brit and a Dutch guy go for a walk. That may sound like the beginning of a joke, but it’s actually the end of a USC-led study that could impact future research on physical activity. With the help of fitness-tracking devices, an international team of scientists studied how physically active people consider
A Purdue University-affiliated startup has devised a way to map arteries in the roof of a person’s mouth to help avoid complications and improve outcomes in oral surgery. Starfish Engineering LLC has developed a method using light to image arteries and lesions through the tissue in the roof of the mouth. Surgeons working in the
Improved information before undergoing PET/CT scanning can improve patients’ experience of care, demonstrates radiology nurse Camilla Andersson in a recent dissertation at Uppsala University. PET/CT scanning is increasingly common for various oncological matters, but it also requires care recipients to understand and follow instructions. Unprepared patients may entail delayed exams and postponed treatment, which can
A new study in the Journal of the National Cancer Institute, published by Oxford University Press, indicates that high-quality cervical cancer screening can be done effectively using a completely automated approach. The researchers involved in the study indicate that automated technology could increase cervical screening coverage in underserved regions. Cervical cancer is caused by persistent
After Utah passed the country’s first law legalizing so-called free-range parenting, groups in states from New York to Texas are pushing for similar steps to bolster the idea that supporters say is an antidote for anxiety-plagued parents and overscheduled kids. Free-range parenting is the concept that giving kids the freedom to do things alone—like explore
(HealthDay)—Whole body computed tomography (WBCT) is not associated with reduced mortality compared with a selective CT approach among children with blunt trauma, according to a study published online April 9 in JAMA Pediatrics. James A. Meltzer, M.D., from the Albert Einstein College of Medicine in Bronx, N.Y., and colleagues conducted a retrospective multicenter cohort study
(HealthDay)—For older adults, dipeptidyl peptidase 4 inhibitors (DPP-4Is) are not associated with increased risk of acute pancreatitis, according to a study published online April 4 in Diabetes Care. Jin-Liern Hong, Ph.D., from the University of North Carolina at Chapel Hill, and colleagues examined the risks of acute pancreatitis among U.S. Medicare beneficiaries, aged 66+ years,
(HealthDay)—Parents, you may be able to stop feeling guilty about letting your toddlers play video games—as long as you’re playing with them. That’s the suggestion of a small study on the effects of touchscreen technology on kids’ development. The research dovetails with growing concern that toddlers might be harmed as technology takes center stage in
The U.S. Coast Guard announced on Monday that it would join the Department of Defense on its EHR project to transition the patient records of its service members and clinics to the DoD’s MHS Genesis platform. The Coast Guard’s needs will be incorporated into the DoD’s $4.3 billion contract with Leidos, rather than signing a
The results of an international clinical trial for a new system of diagnosing heart transplant rejection and injury will be presented publicly for the first time at the International Society for Heart & Lung Transplantation (ISHLT) annual meeting, which will take place on April 11 and 12 in Nice, France. Led by Dr. Phil Halloran
Adding the monoclonal antibody drug trastuzumab—already used to treat certain breast cancers—to the chemotherapy regimen of women with a rare form of uterine cancer lengthens the amount of time their tumors are kept from growing, according to Johns Hopkins Medicine researchers conducting a small phase II trial of the regimen, testing its safety and value.
Spine deformities, such as idiopathic scoliosis and kyphosis (also known as “hunchback”), are characterized by an abnormal curvature in the spine. The children with these spinal deformities are typically advised to wear a brace that fits around the torso and hips to correct the abnormal curve. Bracing has been shown to prevent progression of the
Patients with one or more high-risk clinical features (tearing pain, hypotension, pulse deficit, neurologic deficit, new murmur) should be considered high risk for acute aortic dissection (AAD). That is the finding of a study to be published in the April 2018 issue of Academic Emergency Medicine (AEM), a journal of the Society for Academic Emergency
The U.S. Department of State has released a request for information for a new electronic health record last week, stemming from a failed joint EHR implementation with the Coast Guard. The Coast Guard had attempted to share a hosted EHR with the State Department, known as the Integrated Health Information System, or IHiS. But the
We and our partners use cookies on this site to improve our service, perform analytics, personalize advertising, measure advertising performance, and remember website preferences.Ok