Tag: Addiction

Scientists hunt down the brain circuit responsible for alcohol cravings: Study may open the door to developing drug therapies or even gene therapies for alcohol addiction

Scientists at Scripps Research have found that they can reverse the desire to drink in alcohol-dependent rats — with the flip of a switch. The researchers were able to use lasers to temporarily inactivate a specific neuronal population, reversing alcohol-seeking behavior and even reducing the physical symptoms of withdrawal. “This discovery is exciting — it

Different brain areas linked to smoking and drinking

Academics at the University of Warwick have found that low functional connectivity of the lateral orbitofrontal cortex that is associated with the tendency to smoke is associated with increased impulsiveness — which may contribute to the tendency to smoke. The high connectivity of the reward-related medial orbitofrontal cortex in drinkers may increase the tendency to

Addiction treatment: First steps, types, and medications

However, as a chronic disease, addiction is difficult to treat and requires on-going care. In the United States, around 8.1 percent of the population, or 21.7 million people, either need or regularly receive treatment for substance use disorders, according to the National Survey on Drug Use and Health. First steps The first step towards recovery

Deaths due to tainted herbal medicine under-recorded

A University of Adelaide forensic pathologist is warning that potentially harmful substances found in herbal medicines may be playing a bigger role in deaths of ‘health tourists’ than previously thought. Professor Roger Byard is calling for closer checks during post-mortems for the presence of drugs and adulterants that originate from herbal remedies. “There is a

Cancer drug and antidepressants provide clues for treating brain-eating amoeba infections

The amoeba Naegleria fowleri is commonly found in warm swimming pools, lakes and rivers. On rare occasions, the amoeba can infect a healthy person and cause severe primary amebic meningoencephalitis, a “brain-eating” disease that is almost always fatal. Other than trial-and-error with general antifungal medications, there are no treatments for the infection. Researchers at Skaggs

Sugar pills relieve pain for chronic pain patients: Placebo benefits can be predicted by brain anatomy and psychological traits

Someday doctors may prescribe sugar pills for certain chronic pain patients based on their brain anatomy and psychology. And the pills will reduce their pain as effectively as any powerful drug on the market, according to new research. Northwestern Medicine scientists have shown they can reliably predict which chronic pain patients will respond to a

Newly developed therapeutic shown to combat drug addiction

A new therapeutic may help reverse chemical imbalances made to the brain by habitual drug use and could one day help recovering drug addicts avoid future drug use. Researchers from The University of Texas Medical Branch at Galveston developed and tested a treatment on rats and found it effective in reducing the animals’ cravings. Their

Nicotine alters neurotransmission in habit-forming brain region: Nicotine reduces dorsal striatal output, which may underlie urge to smoke and make it difficult to break the habit

A study of rat brain slices published in JNeurosci demonstrates how nicotine interacts with cells that regulate the output of a brain region involved in habit formation. The research could inform efforts to help people quit smoking and avoid relapse. The addictive qualities of nicotine have been attributed to the brain’s reward system. However, recent

Adolescent binge drinking disrupts mouse memory in adulthood: Study could help scientists better understand development of alcohol use disorders in adults

Excessive drinking during adolescence may interfere with the activity of brain cells needed for sustaining short term memory, according to new research in adolescent male mice published in JNeurosci. The study could help scientists better understand the development of alcohol use disorders in adults. The prefrontal cortex (PFC) and the behavior-management abilities it supports —

In the addiction battle, is forced rehab the solution?

The last thing Lizabeth Loud, a month from giving birth, wanted was to be forced into treatment for her heroin and prescription painkiller addiction. But her mother saw no other choice, and sought a judge’s order to have her committed against her will. Three years later, Loud said her month in state prison, where Massachusetts

Magnetic stimulation dampens brain response to drug cues in addiction

In a study investigating the use of transcranial magnetic stimulation (TMS) for drug addiction, researchers at Medical University of South Carolina are the first to demonstrate that the noninvasive brain stimulation technique can dampen brain activity in response to drug cues in chronic alcohol users and chronic cocaine users. The findings are published in Biological

Prescription drug monitoring programs may have negative unintended consequences: Study shows programs may be linked to fatal drug overdoses

Prescription drug monitoring programs (PDMPs) are a key component of the President’s Prescription Drug Abuse Prevention Plan and considered a critical tool for reducing prescription opioid-related illness and death. The results of a study just conducted at Columbia University’s Mailman School of Public Health and University of California, Davis, show there is insufficient evidence to

Revisiting existing drugs finds molecules that control body clocks: Discovery of an anti-aging supplement that reduces jet lag in mice

Using drug repurposing, a team of researchers led by animal biologists at Nagoya University has discovered compounds that can either shorten or lengthen the circadian rhythm in human cells. A hormone, also known as a common anti-aging supplement demonstrated period-shortening activities, and when it was fed to mice, jet lag symptoms were significantly reduced. Further