Amyloid plaques are aggregates of misfolded proteins that form in the spaces between nerve cells. These abnormally configured proteins are thought to play a central role in Alzheimer's disease. The amyloid plaques first develop in the areas of the brain concerned with memory and other cognitive functions. The amyloid hypothesis Amyloid plaques form when pieces
Alzheimer’s disease is characterized by the presence of beta-amyloid plaques and neurofibrillary tangles of tau, that together lead to the progressive neurodegeneration of neurons in the brain leading to the symptoms of dementia. Image Credit:Atthapon Raksthaput Recent research has revealed that patients and animal models of Alzheimer’s disease display significant disturbances to brain blood flow
The research also demonstrated that statin users had a 23 per cent reduction in the risk of stroke, which is three times more likely in patients with mild dementia and seven times more likely in those with severe dementia. The use of statins is significantly associated with a reduction in the risk of mortality in
Despite the investment of hundreds of millions of dollars over the past several decades on the part of pharmaceutical companies, we still don’t have any meaningful treatment for Alzheimer’s disease. In fact, in a recent extensive study just published in the Journal of the American Medical Association, the two most commonly prescribed medications for Alzheimer’s
There are diseases or problems we tend to associate with older people but unfortunately, they can happen at any time. Here’s what to be aware of… Arthritis It’s a common misconception that arthritis is an old person’s disease. While osteoarthritis is caused by wear and tear, and therefore most common among those over 65, rheumatoid
Scientists have found up to two times higher level of human herpes virus among people with Alzheimer’s disease, suggesting the potential role of the viruses in the development of the progressive brain disorder. Herpes virus causes contagious sores, most often around the mouth or on the genitals. The study found unusually increased level of human
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