Tag: Alzheimer’s Research

Two new studies published by investigators from Brigham and Women’s Hospital illustrate that not all forms of amyloid-beta (Aβ) protein — the protein thought to initiate Alzheimer’s disease — play an equally menacing role in the progress of the disease. Using a new way of preparing and extracting the protein as well as a new

An e-learning programme that trains care home staff to engage in meaningful social interaction with people who have dementia improves wellbeing and has sustained benefits. The average person with dementia in a care home experiences just two minutes of social interaction each day. They also showed that out of 170 available training programmes for nursing

Aging vessels connecting the brain and the immune system play critical roles in both Alzheimer’s disease and the decline in cognitive ability that comes with time, new research reveals. By improving the function of the lymphatic vessels, scientists at the University of Virginia School of Medicine have dramatically enhanced aged mice’s ability to learn and

Commonly-prescribed opioid-based painkillers led to harmful side effects tripling in people with dementia. Researchers from the University of Exeter, King’s College London and the University of Bergen are presenting two studies at the Alzheimer’s Association International Conference 2018 (AAIC) highlighting a significant increase in harmful side effects related to the use of commonly prescribed opioid

A derivative of turmeric could be used in eye drops to treat the early stages of glaucoma, finds a new study led by UCL and Imperial College London researchers. In the new Scientific Reports paper, the researchers report a new method to deliver curcumin, extracted from the yellow spice turmeric, directly to the back of

New research in humans demonstrates the potential to improve memory with a non-invasive brain stimulation technique delivered during sleep. The results, published in JNeurosci, come from a project funded by the United States Department of Defense that aims to better understand the process of memory consolidation, which could translate into improved memory function in both

Researchers at Cold Spring Harbor Laboratory (CSHL), working in collaboration with DepYmed Inc., a CSHL spinout company, today report that they have conducted promising preclinical experiments on a compound that could be used to treat Wilson’s disease and possibly other disorders — including certain types of cancer — in which levels of copper in the

A tailored lighting intervention in nursing homes can positively impact sleep, mood and behavior for patients with Alzheimer’s disease, according to preliminary findings from a new study. People with Alzheimer’s disease and related dementias may experience sleep problems, wandering, and associated daytime irritability. This study tested whether a tailored daytime lighting intervention could improve sleep

A large international study led by a Hamilton researcher has found a patient-centric treatment that works for people with mild asthma. People with mild asthma are often prescribed a daily treatment regimen, but up to 80 per cent do not follow the routine, using inhalers only when they have an asthma attack. Now the researchers

An article published in Nature Medicine with the collaboration of the research group of Dr. Manel Esteller, director of the Epigenetics and Cancer Biology Program of the Bellvitge Biomedical Research Institute (IDIBELL), ICREA Researcher and Professor of Genetics of the University of Barcelona, and Drs. Dave Monk and Isidre Ferrer, from the same center, shows

Starting to play tackle football before age 12 could lead to earlier onset of cognitive and emotional symptoms among athletes who were diagnosed with CTE and other brain diseases postmortem, according to a new study. The findings, from researchers at VA Boston Healthcare System (VABHS) and Boston University (BU) School of Medicine, found that among

Alzheimer’s disease currently affects more than 5.5 million Americans and is one of the costliest diseases to treat, according to the Alzheimer’s Association. Characterized by a buildup of plaque in the brain, few animal models exist that researchers could use to study this devastating disorder. Now, a team of researchers from the University of Missouri,

Kyoto University scientists are one step closer to designing porous materials that can change and retain their shapes — a function known as shape-memory effect. Shape-memory materials have applications in many fields. For example, they could be implanted in the body and then induced to change shape for a specific function, such as serving as

The rate at which the protein beta-amyloid accumulates into the sticky plaques associated with Alzheimer’s disease (AD) is already slowing by the time a patient would be considered to have preclinical AD, according to a longitudinal study of healthy adults published in JNeurosci. The research suggests that anti-amyloid therapies would be most effective before individuals

Patients with Alzheimer’s disease and other forms of dementia commonly experience the sundown syndrome — a sudden worsening of confusion, agitation and aggression at the end of the day. Its daily pattern suggested that “sundowning,” as the phenomenon is also known, may be governed by the body’s internal biological clock. Synchronized by light and darkness,