Tag: associated

MONDAY, Dec. 3, 2018 — Though common breast cancer variants indicate increased breast cancer risk, certain rare variants are associated with an increased risk for interval breast cancers and death, according to a study published in the Nov. 1 issue of Cancer Research. Jingmei Li, Ph.D., from the Genome Institute of Singapore, and colleagues assessed

Researchers at RCSI (Royal College of Surgeons in Ireland) have revealed that one quarter of suicide attempts are associated with dysfunction in how the brain interprets basic perceptual information, such as what we see, hear and think. The research shows that this dysfunction can predict suicidal behaviour, and offers new prospects for treatment and suicide

For decades, scientists have examined how regions of the brain communicate to understand autism. Researchers at University of Utah Health believe the symptoms of autism may result from sustained connections between regions of the brain. The details of their study are available November 16 in the journal JAMA Network Open. “People with autism do not

Patients hospitalized with a cardiovascular event are more likely to die within one year if they have low health literacy, according to a Vanderbilt University Medical Center study released today in Mayo Clinic Proceedings. Health literacy is the ability to access and use reliable health information to make decisions, according to the study’s lead author

People with higher iron levels may be at greater risk of certain types of stroke, a new study has found. Researchers from Imperial College London analysed genetic data from over 48,000 people and revealed that higher iron levels are associated with an elevated risk of a certain type of stroke, called a cardioembolic stroke. These

Violent video game play by adolescents is associated with increases in physical aggression over time, according to a Dartmouth meta-analysis published in the Proceedings of the National Academy of Sciences (PNAS). Although most researchers on the subject agree that playing violent video games appears to increase physical aggression, a vocal minority continues to dispute this.

Imagine a situation where one child is teasing another. While the child doing the teasing means it playfully, the other child views it as hostile and responds aggressively. Behavior like this happens all the time with children, but why some react neutrally and others act aggressively is a mystery. In a new study, a University

Long-term use of coal, wood, or charcoal for cooking is associated with an increased risk of death from cardiovascular disease, according to a study presented today at ESC Congress 2018. Dr. Derrick Bennett, study author, University of Oxford, UK, said: “Our study suggests that people who use solid fuels for cooking should switch to electricity

Middle-aged men who sleep five hours or less per night have twice the risk of developing a major cardiovascular event during the following two decades than men who sleep seven to eight hours, according to research presented today at ESC Congress 2018. Study author Ms Moa Bengtsson, of the University of Gothenburg, Sweden, said: “For

In a study published today in Science, UT Southwestern and Rockefeller University researchers used advanced microscopes to determine at atomic resolution the structure of a molecular complex implicated in birth defects and several cancers. The Hedgehog signaling pathway, which transmits information to embryonic cells, is crucial to human health. Insufficient signaling during development leads to

Epstein-Barr Virus (EBV) doesn’t directly cause cancer, but infection with this common herpes virus brings an increased risk of some cancers, including fast-growing lymphomas. This week in mSphere, researchers report on a new drug that works by targeting EBV-positive tumors. In experiments on mice, the drug inhibited tumor development and metastases for EBV-related lymphomas. The

Oxygen deprivation associated with preterm birth leaves telltale signs on the brains of newborns in the form of alterations to cerebellar white matter at the cellular and the physiological levels. Now, an experimental model of this chronic hypoxia reveals that those cellular alterations have behavioral consequences. Chronic sublethal hypoxia is associated with locomotor miscoordination and

In the first review of its kind, new research has found that depression and the use of antidepressants are each associated with an increased risk of venous thromboembolism (VTE). The study led by academics from the Musculoskeletal Research Unit at the University of Bristol has also shown that each of the various classes of antidepressant

Short- and long-term depressive symptoms can predict the occurrence of cardiovascular events, according to a new study by University of Maine researchers. In addition, short-term or baseline depressive symptoms increase risk for cardiovascular events for up to 15 years, and chronic depressive symptoms for up to 10 years. The study by the UMaine research team—Emily

Further exploration into the endpoints of the NRG Oncology/RTOG 0424 trial resulted in the discovery that MGMT promoter methylation is an independent prognostic biomarker of high-risk, low-grade glioma treated with temozolomide and radiation. This is the first study of its kind to validate the prognostic significance of MGMT promoter methylation in this patient population and

A study led by Luísa Lopes, Group Leader at Instituto de Medicina Molecular João Lobo Antunes (iMM; Portugal) and published today in the prestigious journal Molecular Psychiatry, describes a new mechanism involved in memory loss associated with aging. The work developed over three years by a team of Portuguese, French and German scientists now shows

Reviewing medical information gathered on more than 6,000 adults over a 10-year period, Johns Hopkins researchers have found that lower than normal blood levels of vitamin D were linked to increased risk of early signs of interstitial lung disease (ILD). Interstitial lung disease is a relatively rare group of disorders characterized by lung scarring and

Austrian researchers have discovered that a small number of patients taking targeted drugs known as Janus kinase (JAK) inhibitors to treat myelofibrosis may develop aggressive lymphomas. They also speculate that screening for a preexisting B-cell clone before starting therapy may help prevent this side effect and potentially save lives, according to a study published online

To diagnose rheumatoid arthritis, antibodies to the amino acid citrulline are commonly measured. A new study from Uppsala University shows that a broad mix of different antibodies in the joints is the dominant factor that can be associated with severe inflammation and joint damage. These findings, published in Annals of the Rheumatic Diseases, may eventually

A new study has shown that women who gave birth as adolescents tend to have a greater chance of an early menopause or a hysterectomy. The study, which looked at reproductive histories of women from several countries and income groups, is presented at the World Congress of Menopause in Vancouver. There is increasing evidence that