Stopping the cannibalistic behavior of a well-studied enzyme could be the key to new drugs to fight age-related diseases, according to a new study published online in Nature Cell Biology. For the first time, researchers in the Perelman School of Medicine at the University of Pennsylvania show how the self-eating cellular process known as autophagy
Parents of an 11-month-old girl with a balloon-like growth on her head are desperately trying to find a surgeon who can remove the bizarre mass MK Cruz, from Manila in the Philippines, is thought to have hydrocephalus She needs multiple surgeries to remove the growth and reconstruct her skull Her parents are raising money to
Impeding VCAM1, a protein that tethers circulating immune cells to blood vessel walls, enabled old mice to perform as well on memory and learning tests as young mice, a Stanford study found. Mice aren’t people, but like us they become forgetful in old age. In a study published online May 13 in Nature Medicine, old
Researchers at the San Diego branch of the Ludwig Institute for Cancer Research at University of California San Diego, with colleagues around the country, report that inhibiting activity of a specific protein in glioblastomas (GBM) boosts their sensitivity to radiation, thus improving treatment prospects for one of the most common and aggressive forms of brain
A team of researchers affiliated with several institutions in the U.S. and one in the U.K. has found that blocking a certain inflammatory pathway in mice protects tendons from injury. In their paper published in the journal Science Translational Medicine, the group describes their study of tendinopathies and possible ways to prevent them. Most people
A new study, led by the University of Chicago in Illinois, has unraveled the role of glycogen in fueling ovarian cancer spread. It is the first to reveal how tumor cells interact with support cells called cancer-associated fibroblasts to make this happen. “No systematic study,” says senior study author Ernst Lengyel, who is a professor
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