The combination of taselisib and fulvestrant has shown to slow the growth of cancer in post-menopausal women with estrogen receptor (ER)-positive, human epidermal growth factor receptor-2 (HER2) negative, PIK3CA-mutant, inoperable, locally advanced or metastatic breast cancer. Researchers from Memorial Sloan Kettering Cancer Center (MSK) presented this data, from the SANDPIPER trial, in a press conference
The targeted drug sunitinib (Sutent) is as effective alone as when it’s combined with surgery for some people with advanced kidney cancer, according to a clinical trial. This means some people whose kidney cancer has spread could in future avoid having surgery to remove the affected organ. Average survival times were as good in patients
A test that analyzes free-floating DNA in the blood may be able to detect early-stage lung cancer, a preliminary report from the ongoing Circulating Cell-Free Genome Atlas (CCGA) study suggests. The findings, from one of the first studies to explore whether sequencing blood-borne DNA is a feasible approach to the early cancer detection, will be
Mother with incurable breast cancer is forced to raise £1,000 each month for a drug not available on the NHS because she ‘is not ready’ to say goodbye to her three children Lesley Kennedy, of Belfast, is now taking palbociclib to keep her alive for longer It is hailed as the ‘closest thing to a
An antifungal medication, commonly prescribed for toenail infections, could help eliminate dormant cells within bowel tumours, according to new research funded by Cancer Research UK and published in the Journal of Experimental Medicine today. Researchers at the Cancer Research UK Cambridge Institute have shown in laboratory studies in mice, that itraconazole effectively halts the growth
Common chemical used in plastic packaging and disposable cups is ‘probably carcinogenic for humans’, the World Health Organisation has warned Styrene, a chemical used to make rubber and plastics, is ‘probably carcinogenic’ Its rating was upgraded from possibly cancer-causing after thorough research Exposure to the chemical at work raises risk of leukaemia and nasal cancer
The American Cancer Society released new colorectal cancer screening guidelines today, suggesting that testing begin at age 45 rather than 50 for people at average risk of the disease. The change comes just over a year after ACS researchers reported a dramatic uptick in colorectal cancer cases in younger adults: Compared to people born in
Our immune system’s arsenal of defenses usually protects us from cancer. But sometimes, cancer cells overwhelm or evade this elaborate defense system. In the lab of biochemist and immunologist Christoph Rader, Ph.D., associate professor at The Scripps Research Institute in Florida, scientists have engineered a new type of anti-cancer antibody, one intended to enhance nature’s
The concept of survival of the fittest most often applies to the competition that occurs within and between animal species, but evolutionary pressures can be found elsewhere—even in a cancerous tumor. Cancer researchers have come to understand tumors not as lumps of identical cells, but rather as diverse, dynamic populations unto themselves. And, like individuals
Is it safe to get a "base tan" in the summer? No. There is no safe amount of tanning. Tanning isn't bad for you just because it comes with the risk of burning, which can cause skin cancer. Tanning is bad for you because your body doesn't even begin to tan until dangerous ultraviolet (UV)
In the United States, skin cancer is the most common form of cancer. In 2014 alone, there were almost 80,000 new cases, and by the end of 2018, it is estimated that there will be more than 90,000. Understanding the risk factors behind every type of cancer is important in our effort to minimize the
Anyone who’s taken a bite of a sandwich with too much spicy mustard or a piece of sushi with too much wasabi can attest to the tear-inducing sensation these condiments can cause. These loud warnings to the nervous system of exposure to potentially harmful chemicals are triggered by TRPA1, a calcium channel protein sometimes referred
Some 15,000 new cancer cases are diagnosed in Brazil each year, and researchers have found that approximately 4 percent of these cases could be avoided by reducing overweight and obesity. The epidemiological study was conducted by scientists at the Preventive Medicine Department of the University of São Paulo’s Medical School (FM-USP) in Brazil in collaboration
Mutations to the protein tau, commonly associated with neurodegenerative disorders, may serve as a novel risk factor for cancer, according to results published in Cancer Research, a journal of the American Association for Cancer Research. “Our study revealed that the presence of tau mutations raises the risk of developing cancer,” said Fabrizio Tagliavini, MD, scientific
A collaborative study between the American Cancer Society and the National Cancer Institute finds rates of lung cancer, historically higher among men than women, have flipped among whites and Hispanics born since the mid-1960s. The authors of the study, which appears in the New England Journal of Medicine, say future research is needed to identify
Anyone who’s been through cancer treatment knows: it’s not for sissies. While doctors focus on eradicating tumors and clearing out lymph nodes, patients must deal with the day-to-day discomforts that treatments can cause. A stiff upper lip gets one only so far. Sometimes, trying to be strong backfires, as a body in pain has fewer
In a BJS (British Journal of Surgery) analysis of 18,730 older patients with oestrogen receptor- positive breast cancer in the UK, the risk of dying from breast cancer was greater in patients treated with primary endocrine therapy than in those who received surgery. For the study, researchers analysed cancer registration data from two English regions
Publication in Nature Cell Biology: researchers at the Université libre de Bruxelles, ULB define for the first time the mechanisms responsible for the mammary gland development. The mammary gland is the tissue that produces the milk during lactation, allowing the survival of young mammalian offspring. The mammary gland is composed of two main lineages: the
A national retrospective study led by researchers at The University of Texas MD Anderson Cancer Center found no association between intensity of post-treatment surveillance and detection of recurrence or overall survival (OS) in patients with stage I, II or III colorectal cancer (CRC). Published in the Journal of the American Medical Association, the study is
The latest Annual Report to the Nation on the Status of Cancer finds that overall cancer death rates continue to decline in men, women, and children in the United States in all major racial and ethnic groups. Overall cancer incidence, or rates of new cancers, decreased in men and were stable in women from 1999
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