Tag: Cancer

Kidney cancer, one of the ten most prevalent malignancies in the world, has increased in incidence over the last decade, likely due to rising obesity rates. The most common subtype of this cancer is “clear cell” renal cell carcinoma (ccRCC), which exhibits multiple metabolic abnormalities, such as highly elevated stored sugar and fat deposition. By

A type of molecular ‘rabble-rouser’ that triggers pancreatic cancer to become aggressive and spread around the body has been identified by scientists. The team behind the early-stage research, led by Imperial College London and funded by Pancreatic Cancer UK, say the findings may open avenues for treatments that target these molecules. The molecules, called microRNAs,

Imagine how much patients could benefit if you could discover the presence of cancer, and even how that cancer develops over time, with a simple blood test. There is vast potential in precision-medicine methods of both detecting and monitoring disease by looking for indications of cancer mutations in cell-free DNA (cfDNA), found floating in the

Almost 48,000 men are diagnosed with prostate cancer in the UK every year. But questions are being asked of the tests used to diagnose these men, and how they might be improved. The tests used today can be painful, invasive and, unfortunately, not that good at telling doctors for sure which cases need urgent attention,

The majority of patients eligible for cancer immunotherapy drugs known as checkpoint inhibitors received treatment within a few months of FDA approval, according to a new Yale-led study. The finding suggests that cancer immunotherapies are adopted at a much quicker pace than is typical for newly approved medical treatments, the researchers said. However, patients receiving

Lung cancer is the second most prevalent form of cancer in men and women and the top cancer killer among both sexes. The American Cancer Society (ACS) estimate that in 2018, 154,050 people in the United States will have died from the disease. The World Health Organization (WHO) suggest that 1.69 million deaths are brought

Two patients with mycosis fungoides (MF) can appear to have identical diseases upon first diagnosis but can have radically different outcomes. MF in an unusual cancer of the T lymphocyte that begins in the skin rather than in the lymph nodes, with the first sign often being a rash. Most patients with MF, the most

Prostate cancer is the commonest form of cancer in the Western world. Between 15 to 20 percent of men are affected by it at some time in their lives and 2.6 percent die from prostate cancer. That equates to 1,000 deaths a year in Austria. Apart from genetic factors, environmental (epigenetic) risk factors also play

Parenting concerns contributed significantly to the psychological distress of mothers with late-stage cancer, according to a study by University of North Carolina Lineberger Comprehensive Cancer Center researchers. Cancer is the leading cause of disease-specific death for parenting-age women in the United States, and women with incurable cancer who have children can have increased rates of

Parenting concerns contributed significantly to the psychological distress of mothers with late-stage cancer, according to a study by University of North Carolina Lineberger Comprehensive Cancer Center researchers. Cancer is the leading cause of disease-specific death for parenting-age women in the United States, and women with incurable cancer who have children can have increased rates of

During a stroke or an epileptic seizure, neurons in affected parts of the brain fire at an abnormally rapid rate. One byproduct of this condition is that the pH of the brain drops markedly, rendering the local environment inhospitably acidic. Using a powerful microscopy method called cryo-EM, biologists at Cold Spring Harbor Laboratory (CSHL) have

Plant scientists have taken the crucial last steps in a 60-year quest to unravel the complex chemistry of Madagascar periwinkle in a breakthrough that opens up the potential for rapid synthesis of cancer-fighting compounds. The team in the laboratory of Professor Sarah O’Connor at the John Innes Centre have, after 15 years of research, located

(HealthDay)—Two anti-cancer drugs administered together have been approved by the U.S. Food and Drug Administration to treat an inherited form of thyroid cancer. Tafinlar (dabrafenib) and Mekinist (trametinib) combined have been approved to treat anaplastic thyroid cancer caused by an abnormal BRAF V600E gene, the agency said Friday in a news release. Anaplastic thyroid cancer

Genome-wide association studies (GWAS) have identified more than 150 genetic variations associated with increased risk for breast cancer. Most of these variants are not located in protein-coding gene regions but are assumed to regulate the expression of certain genes. One way to figure out what these variants are doing is to conduct a cis-eQTL analysis.

Researchers from the Novo Nordisk Foundation Center for Protein Research at the Faculty of Health and Medical Sciences have characterised a new protein that is important to the genetic stability of cells. It may be significant for the development of new drugs against genetically determined diseases like cancer, sterility and premature ageing. All cell nuclei

A letter from three University of Chicago researchers in this week’s New England Journal of Medicine updates a 47-year-old series of reports on the risks of exposure during pregnancy to a supplement, diethylstilbestrol (DES), that was once widely used but since 1971 has been linked to a rare cancer: clear-cell adenocarcinoma of the vagina and

Move every day, cut down on oil and stick to one glass of wine: Proven things that DO lower your risk of breast cancer One in eight women will be diagnosed with breast cancer during her lifetime But there are steps you can take to reduce your risk of the deadly disease Exercising at least

Cancer patients are commonly treated with the maximum dose they are able to withstand that does not cause too many toxic side effects. However, many patients become resistant to these treatments and develop cancer recurrence. Researchers at Moffitt Cancer Center are using mathematical modeling based on evolutionary principles to show that adaptive drug treatments based

New research published in Cancer Immunology Research by Drs. Esteban Celis and Hussein Sultan of the Georgia Cancer Center at Augusta University could serve as the stepping-stone in constructing vaccines with a greater likelihood of finding and attacking tumors in the human body. According to Celis and Sultan, the key in this vaccine strategy is

Improved care for patients undergoing cancer surgery is the focus of a pioneering worldwide study. Doctors say the initiative—funded by the National Institute for Health Research (NIHR) – will enable them to gauge surgery quality across the globe and highlight ways to improve patient care. Some 16 million people worldwide will be diagnosed with cancer