Tag: Cancer

Mechanism of resistance to BRAF inhibitors in melanoma identified: A conserved stress response mechanism leads to BRAF inhibitor resistance through AP-1 activation

Melanoma is one of the most aggressive types of skin cancer, but recent advances in targeted therapies have improved the prognosis for many patients. Unfortunately, for some patients these positive outcomes are not long lasting, due to the development of drug resistance and tumor recurrence. Moffitt Cancer Center researchers have discovered a mechanism by which

Woman’s bizarre rash is given diagnosis of anal cancer

The unusual rash that turned out to be a sign of anal cancer: Woman, 73, went to doctors concerned about the spiral patches on her buttocks and back… only to be given the devastating news The woman had the strange rash for 11 months before seeing a doctor   But then she started experiencing vomiting, diarrhoea

Breakthrough in knowledge of how some sarcomas arise

The origin of certain cancers in the sarcoma group is associated with a hitherto unknown interaction among different proteins. Findings now being presented create the opportunity to test new treatments of these forms of sarcoma. “We now know which mechanisms to shine the spotlight on,” says Pierre Åman, Professor of Tumor Biology at Sahlgrenska Academy,

New insights into the development and therapy of cancer

Oncologists at the University and University Hospital in Tübingen have discovered a new protein variant that plays an important role in the development and therapy response of cancer. For physicians, this discovery opens up the opportunity for new options in the diagnosis and therapy of cancer. The results of the study were published on Tuesday,

Prostate cancer rates and deaths have plummeted worldwid

Prostate cancer and death rates have plummeted worldwide, study reveals About one in nine men develop prostate cancer over the course of their lives  In 1994, a blood test for the cancer was approved by the FDA  But the test led to over-diagnosis and has fallen out of favor  In 44 countries, prostate cancer rates

Will There Ever Be a Universal Test to Detect Cancer?

ATLANTA — Cancer is over one hundred different diseases hiding under one name. That's why, just as there isn't one universal way to treat cancer, there also isn't one universal way to detect it. But that doesn't mean scientists aren't trying: If researchers can find a unique signature or "biomarker" of cancer — meaning a

Helping infants survive brain cancer

Choroid plexus carcinoma (CPC) is a particularly challenging type of brain cancer. The tumor most commonly arises in infants under the age of one—who are too young to undergo radiation treatment. Only 40 percent of children remain alive five years after diagnosis, and those who do survive often suffer devastating long-term damage from the treatment.

Choose the right colon cancer screening option

(HealthDay)—Colon cancer is highly preventable through regular screening. But the right type of screening depends on your particular risk factors, an expert says. Each year in the United States, more than 140,000 people are diagnosed with colon cancer, and about 50,000 die from the disease. It’s the second-leading cause of cancer death in the country.

Radiomics predicts who will benefit from chemotherapy

Using data from computed tomography (CT) images, researchers may be able to predict which lung cancer patients will respond to chemotherapy, according to a new study published in the journal Radiology: Artificial Intelligence. Platinum-based chemotherapy is typically the first-line treatment of advanced-stage non-small cell lung cancer (NSCLC). However, only about one in four patients responds

How a common oral bacteria makes colon cancer more deadly

Researchers at the Columbia University College of Dental Medicine have determined how F. nucleatum—a common oral bacteria often implicated in tooth decay—accelerates the growth of colon cancer. The study was published online in the journal EMBO Reports. The findings could make it easier to identify and treat more aggressive colon cancers. It also helps explain

Tumor on the heart: these symptoms point to heart cancer

A cardiac tumor is rare but dangerous Although heart diseases are for the most deaths, and cancer is the second, heart cancer is a very rare and little researched disease. Why the heart is so rarely affected by tumor disease, explain American heart specialists. The American heart organization American Heart Association recently reported on the

Tumor on the heart: These Symptoms point to heart cancer

A cardiac tumor is rare but dangerous Although heart diseases are for the most deaths, and cancer is the second, heart cancer is a very rare and little researched disease. Why the heart is so rarely affected by tumor disease, explain American heart specialists. The American heart organization American Heart Association recently reported on the