Tag: Cancer

The CRISPR-Cas9 gene editing system may be able to restore the effectiveness of first-line chemotherapies used to treat lung cancer by deleting or “knocking out” a gene in cancer tumors that helps the tumors develop resistance to the drugs. That was the conclusion of a new study published today in the journal Molecular Therapy Oncolytics

Bowel (colorectal) cancer is the third most commonly occurring cancer in men and the second most commonly occurring cancer in women worldwide. The global burden is expected to increase by 60 per cent to more than 2.2 million new cases and 1.1 million deaths by 2030. The research, which has been published in the Journal

A cancer diagnosis tells you that you have cancer, but how that cancer will progress is a terrifying uncertainty for most patients. Researchers at Cold Spring Harbor Laboratory (CSHL) have now identified a specific class of biomarkers that can tell a lot about how aggressive a patient’s cancer will be. “There are undoubtedly dozens or

Min Dong, PhD, and his lab are world experts in toxins and how to combat them. They’ve figured out how Clostridium difficile‘s most potent toxin gets into cells and zeroed in on the first new botulinum toxin identified since 1969. Now, setting their sights on Shiga and ricin toxins, they’ve not only identified new potential

Five years after diagnosis, only 40 percent of patients with locally-advanced oral cavity cancer will still be alive. The question is who is likely to live and who is likely to die? The answer to this question could not only help patients better predict the course of their disease, but could help doctors choose the

WEDNESDAY, Dec. 5, 2018 — Type 2 diabetes (T2D) is associated with an increased risk for colorectal cancer (CRC), with the association significant for men only, according to a study published online Nov. 7 in the British Journal of Cancer. Yanan Ma, from China Medical University in Shenyang, and colleagues followed 87,523 women from the

A program that provided individually tailored lifestyle recommendations for patients undergoing screening for colorectal cancer helped encourage healthy behavior, according to results published in Cancer Epidemiology, Biomarkers & Prevention, a journal of the American Association for Cancer Research. “It is well known that a healthy lifestyle decreases the risk of colorectal cancer,” said the study’s

Researchers from North Carolina State University have created the largest publicly available virtual library of macrolide scaffolds. The library — called V1M — contains chemical structures and computed properties for 1 million macrolide scaffolds with potential for use as antibiotics or cancer drugs. “As chemists, we’re only able to look at a tiny portion of

A powerful new biochemical platform is fueling the study of a family of enzymes that are promising targets for cancer treatment. Published today in Science Advances, the new method provides a high-resolution view of how these enzymes, called lysine methyltransferases, selectively mark proteins with chemical tags that alter their function. Because of their central role

A unique partnership between a Virginia Tech scientist and a University of Virginia oncologist could result in a solution to reduce discomfort during cancer treatment for women. Tim Long, a professor of chemistry with the Virginia Tech College of Science, and Tim Showalter, a radiation oncologist at UVA’s Cancer Center, are testing a gel that

UC San Francisco scientists have figured out why some lung cancers become drug-resistant after initially responding to targeted therapies. In the process, they devised a new two-pronged approach that yields an effective treatment for these cancers in the laboratory and holds tremendous promise for the future of precision medicine, they said. The findings are detailed

Cancer diagnosis scandal: 17,000 Britons die needlessly every year due to delays in spotting the disease, experts warn Delays in diagnosis means the UK lags behind Europe on cancer survival rates Millions more people need to be sent for testing if Britain is to catch up  Yet GPs are being pressured to become ‘gatekeepers’ and

Previously on Medical News Today, we covered a study explaining that an experience called chemo brain affects many people undergoing cancer — particularly breast cancer — treatment. Chemo brain occurs during cancer treatment, and it may last for a long time after the treatment is over. People experiencing it report a loss of quality in

Using technology similar to the type that powers facial and speech recognition on a smartphone, researchers at the University of North Carolina Lineberger Comprehensive Cancer Center have trained a computer to analyze breast cancer images and then classify the tumors with high accuracy. In a study published in the journal NPJ Breast Cancer, researchers reported

Treatment with capivasertib, a drug designed to work against a particular gene mutation found in some tumours, shows signs of being effective in a trial of 35 patients presented today (Tuesday) at the 30th EORTC-NCI-AACR Symposium on Molecular Targets and Cancer Therapeutics in Dublin, Ireland. The phase 2 trial (EAY131-Y) is part of a larger

NHS knew ‘for a MONTH’ about cervical cancer screening blunder that saw almost 50,000 women miss out on smear test invites and results More than 4,500 women were not sent the results of their screening tests  Whereas more than 40,000 were not sent appointment invitations or reminders  The BMA has called the situation ‘incredibly serious’

A combination of two drugs, which prompt the body’s immune system to identify and kill cancer cells, is a safe treatment for patients with advanced non-small cell lung cancer and has shown some signs of efficacy. Results from a phase I/II clinical trial in 25 patients, presented at the 30th EORTC-NCI-AACR Symposium on Molecular Targets

Scientists at the German Cancer Research Center (Deutsches Krebsforschungszentrum, DKFZ) have now found a cause for the frequent catastrophic events in the genetic material of cancer cells that have only been known for a few years: If an important DNA repair system of the cells has failed, this promotes fragmentation and defective assembly of the

Obesity puts you more at risk of cancer ‘because fat clogs up and slows down the cells that fight off the disease’ Lead ‘Natural Killer’ cells stutter and fail when excess fat blocks their pathways  New research shows the damage can be reversed to kick the cells into action Obesity is the second leading preventable

Protein nanopores are present in cell membranes and act as biological gateways. This means that they can also be used for the detection of specific bioactive molecular chains, like sugar chains, such as molecules from the glycosaminoglycan family. The latter are responsible for key interactions at the cellular level. They typically mediate interactions with cell