Tag: Cancer

Melbourne scientists have discovered how tumour development is driven by mutations in the most important gene in preventing cancer, p53. The research revealed that in the early stages of cancer, mutant p53 ‘tackles’ the normal p53 protein and blocks it from carrying out its protective role. As a result, p53 can no longer activate natural

Researchers have developed a new nuclear medicine tracer that could improve diagnosis and treatment of non-small cell lung cancer. Research published in the November issue of The Journal of Nuclear Medicine found that the new tracer, 99mTc-HYNIC-cMBP, produced clearer images in less time than currently used tracers and was more rapidly eliminated from the body,

THURSDAY, Nov. 1, 2018 — Rats developed cancer after being exposed to high levels of cellphone radiation, but those levels were much higher than what people are exposed to when using their cellphones, a new government report says. When exposed to radio frequency radiation like that used in 2G and 3G cellphones, male rats developed

Rhabdomyosarcoma (RMS) is a rare cancer of the skeletal muscle that primarily affects pediatric patients. After diagnosis, about 3 out of 4 patients are cured with standard treatment. Survival rates drop to 17 percent if the disease comes back (recurs) and to 30 percent if it spreads (metastasizes). “RMS has among the worst survival statistics

Oesophageal microbiota may help to improve the diagnosis and management of oesophageal cancer, according to the results of a study presented today. Researchers from Italy directed by Professor Cammarota have found a unique pattern of microbes living in the oesophagus of people with oesophageal cancer or Barrett’s oesophagus, which could potentially be used to identify

Researchers have discovered a novel consequence of loss of the tumour protein p53 that promotes cancer development, according to new findings in eLife. The study in mouse and human cells, from the Netherlands Cancer Institute, suggests that multiplication of cancer cells in the absence of appropriate growth stimuli is supported by the additional loss of

(HealthDay)—Cancer treatment is associated with a clinically meaningful survival benefit in older, medically complex patients with superficial bladder cancer (SBC), according to a study published online Oct. 5 in Cancer. Tullika Garg, M.D., M.P.H., from Geisinger in Danville, Pa., and colleagues evaluated the association between treatment of SBC and 10-year mortality in 1,800 medically complex

For the first time ever, Mount Sinai researchers have identified a protein as a marker that can indicate whether a cancer patient will develop a reoccurrence of lethal, metastatic cancer, according to a clinical study published in Breast Cancer Research in October. The researchers found that when cells from a breast cancer patient’s original tumor

High levels of air pollutants, especially fine particulate matter (PM2.5) and to a lesser extent, ozone, may be linked to a heightened risk of developing mouth cancer, suggests the first study of its kind, published online in the Journal of Investigative Medicine. The number of new cases, and deaths from, mouth cancer is increasing in

Atrial fibrillation (AFib) patients with a history of cancer are less likely to see a cardiologist or fill anticoagulant prescriptions compared with AFib patients who never had cancer, according to a study in the Journal of the American College of Cardiology. By not filling and taking prescribed medication, these patients are potentially putting themselves at

A doctor may recommend radiation therapy in combination with other treatments, such as surgery and chemotherapy. There are two main types of radiation treatment: External beam radiation: This involves a doctor applying radiation from an external machine to the breast and surrounding tissue. Internal radiation (brachytherapy): This involves placing a small radioactive pellet into the

Researchers at the University of Helsinki have reported PeptiENV, a cancer vaccine platform that can be used to improve the therapeutic efficacy of oncolytic enveloped viruses currently in clinical use. With the help of this new cancer vaccine platform, the activation of the human immune response against cancer cells becomes significantly more effective. “What is

The presence of the human high-risk papillomavirus (hrHPV) in the diagnosis of invasive cervical cancer is linked to a greatly improved prognosis compared to cases in which hrHPV cannot be identified in the tumour, according to researchers at Karolinska Institutet in Sweden, who have published their results in the scientific journal PLOS Medicine. The researchers

A phase I clinical trial investigating the use of bacterial Clostridium novyi-NT spores as an injectable monotherapy had manageable toxicities and showed early clinical efficacy in patients with treatment-refractory solid tumor malignancies, according to data presented at the Fourth CRI-CIMT-EATI-AACR International Cancer Immunotherapy Conference: Translating Science into Survival, held Sept. 30-Oct. 3. “Even after a

Cancer treatment continues to improve for many types of cancer, leading to increased life expectancy for many survivors. In fact, the number of cancer survivors is expected to reach nearly 18 million within the next decade in the U.S.1 For survivors of non-small cell lung cancer (NSCLC), the most common type of lung cancer, their

Cancer needs energy to drive its out-of-control growth. It gets energy in the form of glucose, in fact consuming so much glucose that one method for imaging cancer simply looks for areas of extreme glucose consumption — where there is consumption, there is cancer. But how does cancer get this glucose? A University of Colorado

Prostate cancer is the second most common cancer in American men. But black men bear a disproportionate burden of its effects. It’s more common—and more than twice as deadly—among black men compared to their white counterparts. Yet the United States Preventive Services Task Force (USPSTF) recommendations for prostate cancer screening do not differentiate for race,

Treatment with a HER2-targeted therapeutic cancer vaccine provided clinical benefit to several patients with metastatic HER2-positive cancers who had not previously been treated with a HER2-targeted therapeutic, according to data from a phase I clinical trial presented at the Fourth CRI-CIMT-EATI-AACR International Cancer Immunotherapy Conference: Translating Science into Survival, held Sept. 30-Oct. 3. Among 11

In the United States, ovarian cancer has the highest mortality rate of all gynecologic cancers, according to the Centers for Disease Control and Prevention (CDC). In 2014, for instance, over 21,000 new cases of ovarian cancer occurred, at least 14,000 of which resulted in death. Previous research has suggested that combined oral contraceptives — that

Anal cancer explained: Farrah Fawcett, Marcia Cross and the unspoken HPV cancer killing women as well as men Anal cancer is rare, affecting around 7,000 Americans a year But Google searches about it are soaring after Marcia Cross revealed she is recovering from it Here we explain the cancer, which killed Farrah Fawcett in 2015