A study led by researchers from The University of Texas MD Anderson Cancer Center found a significant association between cholesterol-lowering drugs commonly known as statins and survival rates of triple-negative breast cancer patients. Since statins are low in cost, easy to access and produce minimal side effects, this could have an important impact on outcomes
Most countries have not introduced nationwide prostate-cancer screening, as current methods result in overdiagnoses and excessive and unnecessary biopsies. A new study by researchers at Karolinska Institutet in Sweden, which is published in The New England Journal of Medicine, indicates that screening by magnetic resonance imaging (MRI) and targeted biopsies could potentially cut overdiagnoses by
International organizations and countries around the world are working to eliminate HIV/AIDS by 2030. To reach this goal, new approaches are needed–particularly among difficult-to-reach groups such as people who inject drugs (PWID), who are 30 times more likely to contract HIV/AIDS compared with the general population. Matthew Akiyama, M.D., assistant professor of medicine at Albert
WEHI has partnered with Boehringer Ingelheim, a leading research-driven pharmaceutical company, in a collaboration to discover and develop anti-cancer therapeutics using a promising new technology called targeted protein degradation. The partnership builds on more than 25 years of pioneering discoveries at WEHI, into a family of proteins known as the inhibitor of apoptosis proteins (IAPs)
Researchers at the University of North Carolina at Chapel Hill and the UNC Lineberger Comprehensive Cancer Center have uncovered a new mechanism that activates specific genes, leading to the development of cancers. They showed that a mutation that fuses two unrelated genes can promote a process similar to that observed when oil and water are
It had been a long four years since that July night when Marianne Sarcich first felt the lump in her right breast as she toweled off from a shower. Breast cancer. The cancer was caught early enough that it had not spread to other parts of her body, but doctors said she would need a
Prostate cancer is the most common form of cancer among Canadian men and the third leading cause of cancer death. Abdominal obesity appears to be associated with a greater risk of developing aggressive prostate cancer. This link was demonstrated in a study led by Professor Marie-Élise Parent of Institut national de la recherche scientifique (INRS)
The Translational Genomics Research Institute (TGen), an affiliate of City of Hope, today announced a substantial grant from Taiwan Semiconductor Manufacturing Co. Ltd. (TSMC), one of the world's largest manufacturers of computer chips, to help TGen sustain Arizona's fight against COVID-19. The TSMC grant will boost TGen efforts to track variants of the SARS-CoV-2 virus,
Researchers at the University of Turku, Finland, showed that the antibody treatment reactivates the immune defense in patients with advanced-stage cancer. The treatment alters the function of the body's phagocytes and facilitates extensive activation of the immune system. The immune defense is the body's own defense system equipped to combat cancer. However, cancer learns to
Every tumor is different, every patient is different. So how do we know which treatment will work best for the patient and eradicate the cancer? In order to offer a personalised treatment that best suits the case being treated, a team of scientists led by the University of Geneva (UNIGE), Switzerland, had already developed a
New research indicates that certain anti-cancer therapies may hasten cellular aging, where changes in the DNA of patients may contribute to greater inflammation and fatigue. The findings are published by Wiley early online in CANCER, a peer-reviewed journal of the American Cancer Society. Gene activity is often adjusted during life through epigenetic changes, or physical
A biochemical reaction between an enzyme called luciferase and oxygen causes fireflies to glow and is considered one of the most well-known examples of bioluminescence in nature. Now, an international team of researchers led by Elena Goun at the University of Missouri is working to harness the power of bioluminescence in a low-cost, noninvasive portable
The National Institutes of Health has jointly awarded a $3.9 million grant to Ali Khademhosseini, Ph.D., director and CEO of the Terasaki Institute for Biomedical Innovation (TIBI), and Rami Oklu, Ph.D., M.D., of the Mayo Clinic. The grant will be used to develop innovative drug delivery methods to treat liver cancer. TIBI, a leader in
The hormone prolactin has long been understood to play a vital role in breast growth and development and the production of milk during pregnancy. But a pair of recent studies conducted at VCU Massey Cancer Center finds strong evidence that prolactin also acts as a major contributor to breast cancer development and that the hormone
Home sensors to monitor cancer patients' pain. A smartphone app to manage breast cancer patients' anxiety and depression. And $12 million in new grant funding to pay for even more health care advances, earned from just a $2 million initial investment. These are just a few of the remarkable, positive results of the University of
Some types of cancer may alter the appearance and function of the heart, according to new research that analyzed people’s hearts before cancer treatment. An estimated 1.9 million people in the United States are expected to be diagnosed with cancer this year, according to the National Cancer Institute. Having a history of cancer is linked
(HealthDay)—In new guidelines issued by the American Thyroid Association and published in the March issue of Thyroid, recommendations are presented for the diagnosis, evaluation, and treatment of anaplastic thyroid cancer (ATC). Keith C. Bible, M.D., Ph.D., from the Mayo Clinic in Rochester, Minnesota, and colleagues reviewed the relevant literature to develop guidelines relating to the
A personalized genomic cancer vaccine proved feasible to manufacture and was well tolerated in a phase 1 trial, according to researchers. The vaccine, PGV-001, was given to 13 patients with solid tumors or multiple myeloma who had a high risk of recurrence after surgery or autologous stem cell transplant. At last follow-up, four patients were
A new study co-authored by University of Colorado Cancer Center researcher Srinivas Ramachandran, Ph.D., shows how DNA segments known as enhancers function in cells. The paper published last month in Molecular Cell highlighted the work from Ramachandran, along with Satyanarayan Rao, both part of the Department of Biochemistry and Molecular Genetics at the CU School
Did catching Covid-19 help these patients fight cancer? One saw his tumours vanish, another went into remission. Now doctors are asking if their immune response was key – and if it could also be triggered by the vaccine When doctors at a hospital in Cornwall carried out a follow-up check last summer on a 61-year-old
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