Tag: Cancer

Growing miniature tumors from patient’s cells in the laboratory may help scientists personalize treatments for those with a rare form of prostate cancer, according a study by Weill Cornell Medicine and NewYork-Presbyterian scientists. Patients with prostate cancer often receive therapies that reduce levels of testosterone. Many of their tumors eventually become resistant to such hormone-reducing

A research team found a novel function of fibroblast growth factor 2 (FGF2), a self-renewal factor for spermatogonial stem cell (SSC) which is the origin of the sperm production. Although it has demonstrated that both FGF2 and glial cell line-derived neurotrophic factor (GDNF) is indispensable for SSC self-renewal and survival in vitro, the present study

MONDAY, July 2, 2018 — For patients with previously treated advanced gastric cancer or gastro-esophageal junction cancer, pembrolizumab does not result in a significant improvement in overall survival compared with paclitaxel, according to a study published online June 4 in The Lancet. Kohei Shitara, M.D., from National Cancer Center Hospital East in Kashiwa, Japan, and

A new study published this year has women reconsidering booking in for fresh balayage, after it found that those who use dark hair dye or chemical hair straighteners have a higher risk of breast cancer. Published in medical journal Carcinogenesis, the study looked at more than 4000 women from New York and New Jersey, aged between

For many women diagnosed with breast cancer, genetic testing can offer important information that might guide treatment choices. But studies have shown that only about half of women who could benefit receive genetic testing. A new study finds that surgeons are a key influence. “The surge of genetic testing in cancer care is a major

A potential new target for treatment has been identified in an aggressive form of bladder cancer, Mount Sinai researchers report in a recent study. Bladder cancers are categorized into subtypes based on molecular features. These subtypes are associated with different prognoses and responses to conventional treatments such as chemotherapy. A type of bladder cancer called

Researchers using automated breast density measurements have found that women with mammographically dense breast tissue have higher recall and biopsy rates and increased odds of screen-detected and interval breast cancer, according to a large new study from Norway published online in the journal Radiology. The study supports automated measurements as a future standard to ensure

The overproduction of the BCL-2 protein is due to a defect in the ribosome, the protein factory of the cell. This defect is found in 10% of the pediatric patients with T-cell leukemia. Ribosome defects and cancer “In the past couple of years, it has become clear that ribosome defects play a role in different

Researchers in Sweden have shown how data-driven AI could contribute to a better understanding of how prostate cancer develops, and even improve clinical diagnosis and treatment of the disease. Every cancer tumor is unique, with characteristics that change over time. This so-called heterogeneity is due to competing clones within a given tumor, as well as

Research spearhead by first author Isabel Puig, Post-Doctoral Fellow of the Vall d´Hebron Institute of Oncology’s (VHIO) Stem Cells & Cancer Group, directed by Principal Investigator Héctor G. Palmer, has culminated in the discovery of a biomarker to identify dormant tumor cells (DTC), also known as slow-cycling cancer cells (SCCC), that, in their dormant state,

Researchers at the Johns Hopkins Kimmel Cancer Center and the Bloomberg~Kimmel Institute for Cancer Immunotherapy (BKI) released a study investigating the use of combination checkpoint immunotherapy in the treatment of a lethal form of advanced prostate cancer. The study suggested a genetic subset of prostate cancer may benefit from this form of immunotherapy. The study

A genetic anomaly in certain men with prostate cancer may impact their response to common drugs used to treat the disease, according to new research at Cleveland Clinic. The findings may provide important information for identifying which patients potentially fare better when treated with an alternate therapy. In a newly published study in Journal of

A new microscope system can image living tissue in real time and in molecular detail, without any chemicals or dyes, report researchers at the University of Illinois. The system uses precisely tailored pulses of light to simultaneously image with multiple wavelengths. This enables the researchers to study concurrent processes within cells and tissue, and could

Fighting cancer means killing cancer cells. However, oncologists know that it’s also important to halt the movement of cancer cells before they spread throughout the body. New research, published today in the journal Nature Communications, shows that it may be possible to freeze cancer cells and kill them where they stand. Raymond Bergan, M.D., Division

A cancer treatment already approved for use in certain types of cancer has been found to block cell growth in a common form of lung cancer for which there is currently no specific treatment available. The new findings, published today in Science Translational Medicine and led by the University of Glasgow, suggest that a large

Giving the drug sodium thiosulphate after chemotherapy reduces hearing loss in children treated for liver cancer, according to findings published in the New England Journal of Medicine today. Results from the Cancer Research UK funded SIOPEL-6 clinical trial show that giving sodium thiosulphate (STS), after a type of chemotherapy called cisplatin, reduces hearing loss by

It’s called the Silver Tsunami—the increased incidence of cancer with ageing, combined with the rapidly ageing population means that the Australian health system needs to prepare for an onslaught of cancer diagnoses. A new study out of Monash University, published today in the journal Cell Reports, may have found a group of immune cells that

Scientists at the Ovarian Cancer Action Research Centre at Imperial College London have discovered a mechanism that deactivates ovarian cancer cells. The findings, published in EMBO Reports, could lead to better treatments for women with ovarian cancer. The research has found a new mechanism for a protein named OPCML. This protein is known as a

Using a targeted therapy to block a protein that suppresses T cell activity could improve cancer treatment with immune checkpoint inhibitors, researchers at The University of Texas MD Anderson Cancer Center report today in the Journal of Clinical Investigation. The team showed that EZH2 is elevated in immune T cells in patients after treatment with

Type 2 diabetes could be early indicator of one of the deadliest forms of cancer. The Journal of the National Cancer Institute released a study on Monday indicating that diabetes after the age of 50 could be an early indicator of pancreatic cancer, one of the deadliest forms of cancer, reported CNN. For 20 years,