A physician-scientist at the University of Arizona Cancer Center investigated a novel treatment for pancreatic cancer patients whose tumors exhibited a harmful genetic mutation. The results, in which a type of drug called a PARP inhibitor showed early promise in treating pancreatic cancer in patients with mutations in the BRCA gene, were published online last
A large proportion of the American public opts to receive cancer screenings with the hope that testing will reduce their chance of cancer death. Now, a team led by University of Missouri psychological science researchers has determined that patients may want cancer screenings even if the potential harms outweigh the benefits. Researchers believe that clinicians
Treatment changes including the advent of targeted and immune therapies have dramatically improved survival for blood cancers, but new report calls for improved evaluation of poorly understood side effects that may develop over time.—- Survival rates for blood cancers—including lymphoma, myeloma and some types of leukaemia—have dramatically increased over the past decade, due in great
(HealthDay)—Eating a nutritionally balanced high-quality diet may lower a cancer patient’s risk of dying by as much as 65 percent, new research suggests. The finding that total diet, rather than specific nutritional components, can affect a cancer patient’s prognosis “was particularly surprising to us,” said the study’s lead author, Ashish Deshmukh. Total diet, he explained,
Proteins commonly known as BRCA—short for BReast CAncer susceptibility gene- serve a critical role in cellular DNA repair, but when mutated they allow genetic errors to replicate, facilitating cancer development. If the BRCA repair system is disabled in cancer cells, the cells simply turn to backup repair mechanisms and adapt to alternative repair pathways, a
How 53-year-old retail worker became one of the first NHS patients to be saved by ‘miracle’ cancer treatment Eighteen months on from successful treatment for an aggressive type of skin cancer, Tina Manning, 53, of Luton, faced the words no patient wants to hear The cancer was back — and it had spread to her brain
An international team of researchers including USC scientists has found scores of new genetic markers in DNA code that increase prostate cancer risk — powerful knowledge likely to prove useful to detect and prevent the disease. Focusing on DNA of more than 140,000 men worldwide, researchers were able to identify 63 new genetic markers associated
You've just claimed a spot on the beach; the sun is rising overhead, and you're looking forward to a relaxing day of sea and sun. And speaking of sun — you mustn't forget to apply a generous layer of protective sunblock. But when you reach for your tube of sunscreen, you notice that it's long
Prostate cancer breakthrough: New DNA test identifies men who are SIX TIMES more likely to develop the disease Researchers identified 63 new genetic mutations linked to the condition Combined with over 100 variants known to cause the cancer to make the test One in 100 men carry sufficient numbers of genetic variations to put them
There are two techniques for creating a mammogram. Film-screen mammography creates a photographic film, while digital mammography creates digital images. Both methods use the same procedure for taking the image. The person having the mammogram will place their breast between two clear plates, which will squeeze it between them to hold it in place. This
Metastatic breast cancer, a term for advanced breast cancer that’s spread to other parts of the body, is a devastating diagnosis: Its average life expectancy is just three years, and its five-year survival rate is just 22%. Tumors can be treated and symptoms can be managed, but most patients fight the disease for the rest
A unique bacterial strain isolated from a patient with pelvic pain may represent a promising path to treating prostate cancer with immunotherapy, according to a Northwestern Medicine study published in Nature Communications. The study demonstrated how the bacterial strain travels directly to the prostate and induces low-level inflammation, boosting the effectiveness of immune checkpoint inhibitor
Last month, Erich Voigt, MD, an ear, nose and throat surgeon in New York, was watching TV, tuned in to HGTV’s Beachfront Bargain Hunt. But instead of checking out the tropical homes, he was drawn to show guest Nicole McGuinness. After noticing an unusual lump on the 32-year-old’s neck, he sent a Facebook message with an alarming warning.
One of the main risk factors for non-melanoma skin cancer (NMSC), the most common cancer worldwide, is solar ultraviolet radiation. A new Journal of the European Academy of Dermatology and Venereology study has found that different outdoor professions carry different risks for NMSC. In the study of 563 participants (47% women) consisting of 348 outdoor
One of the main risk factors for non-melanoma skin cancer (NMSC), the most common cancer worldwide, is solar ultraviolet radiation. A new Journal of the European Academy of Dermatology and Venereology study has found that different outdoor professions carry different risks for NMSC. In the study of 563 participants (47% women) consisting of 348 outdoor
Immunotherapy is a form of cancer therapy that boosts the body’s immune system in the fight against tumors. Adoptive cell transfer (ACT), in particular, is a type of immunotherapy that strengthens a specific kind of immune cell: T cells. In ACT, healthcare professionals collect T cells from the malignant tumor and isolate immune cells that
Scientists have uncovered a completely new way to make cancers sensitive to treatment—by targeting antenna-like structures on cells. Their study found that drug-resistant cancer cells have more and longer antennae than those which are killed by treatment. Blocking the growth of antennae reactivated a range of cancer treatments that had stopped working, the team at
Clinical trial results presented today at a prestigious cancer meeting in Chicago show substantial increased survival rates for pancreatic cancer patients who received a four-drug chemotherapy combination known as mFOLFIRINOX after surgery. Pancreatic cancer is typically very aggressive, with only approximately eight per cent of people surviving beyond five years after diagnosis, even after surgery
Cancer cells in children tend to develop by following four main trajectories — and two of them are linked to relapse of the disease, research led by Lund University in Sweden shows. The four strategies can occur simultaneously in a single tumour, according to the study that is now published in Nature Genetics. The researchers
Premenopausal women with hormone receptor-positive, HER2-negative breast cancer and a high risk of recurrence who are treated with an aromatase inhibitor plus ovarian function suppression may gain 10 to 15 percent improvement in freedom from distant recurrence at eight years, according to a new clinical trial analysis reported at the annual meeting of the American
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