Tag: chronic

Stiffness in our tissues causes tension in our cells. Research from the Buck Institute, the University Health Network (University of Toronto), Stanford University, and the University of Alberta shows that stiffness impacts the innate immune system by upping its metabolism. The findings suggest the cellular tension likely sets off an inflammatory loop that contributes to

Recently, a research team led by Profs. Liu Qingsong and Liu Jing from the Institute of Health & Medical Technology of the Hefei Institutes of Physical Science (HFIPS) discovered a potent and selective PI3Kδ inhibitor IHMT-PI3Kδ-372, effective against chronic obstructive pulmonary disease (COPD) in vivo. COPD is a chronic progressive respiratory disease characterized by airflow

TUESDAY, Oct. 13, 2020 — Among children who are hospitalized, pediatric chronic kidney disease (CKD) is associated with longer length of stay (LOS) and increased costs compared with other chronic illnesses, according to a study published online Oct. 12 in the American Journal of Kidney Diseases. Zubin J. Modi, M.D., from the University of Michigan

A new mass study of people living with chronic pain in the UK has demonstrated the links between pain and certain atmospheric weather conditions. Weather systems in the UK could cause chronic pain suffers to experience more or less pain on certain days as a result of certain pressure patterns and accompanying rain, humidity, and

A bit of stress is a normal part of our daily lives, which can even be good for us. Overcoming stressful events can make us more resilient. But when the stress is severe or chronic—for example caused by the breakdown of a marriage or partnership, death in the family or bullying—it needs to be dealt

A minimally invasive procedure to treat a common foot and ankle disorder can reduce pain, recovery time, and postsurgery complications while improving functional outcomes, according to a report published in the journal Foot and Ankle Surgery. The procedure treats insertional Achilles tendinopathy, a common and chronic orthopedic disorder in which patients experience pain at the

Be it autism, sickle cell or other life-disrupting health conditions, being the parent of a child with a chronic condition takes a psychological toll. For too many families, however, emotional and behavioral health support has been far too difficult to obtain. Now, a project led by experts at Cincinnati Children’s reports on the progress made

Christopher Lee was 15 years old when he was shot May 14, 2016, while on his bike outside his East Garfield Park home. Now 18, Lee was shot in the back, arm and chest, and was in the hospital for six days, where he had two surgeries in addition to staples and stitches. To this

Gulf War Illness (GWI) and chronic fatigue syndrome (CFS) share symptoms of disabling fatigue, pain, systemic hyperalgesia (tenderness), negative emotion, sleep and cognitive dysfunction that are made worse after mild exertion (postexertional malaise). Now, neuroscientists at Georgetown University Medical Center have evidence, derived from human brain studies, that GWI and CFS are two distinct disorders

Until she was 25, Rachel* was completely healthy. She ran marathons and rode horses, and later she was active in her job as a microbiologist. Suddenly, she developed joint problems. She was first diagnosed with Lyme disease, then a genetic condition called Ehlers-Danlos syndrome, which makes her joints move beyond their normal range of motion

The annual cost of chronic pain in the United States is estimated to be more than $635 billion in direct medical costs, lost productivity and disability programs. One in five adults—50 million Americans—report living in chronic pain. The increasing number of patients is leading to a major push to develop non-opioid treatments for chronic pain.

Infectious proteins called prions cause a group of related, fatal and incurable neurodegenerative disorders, including bovine spongiform encephalopathy or Mad Cow disease and Creutzfeldt-Jakob disease, both of which affect humans. Chronic wasting disease or CWD, also caused by prions, has reached the point of a global epidemic among deer, elk and members of the deer

Growing evidence shows that the brain’s dopamine system, which drives motivation, is directly affected by chronic, low-grade inflammation. A new paper proposes that this connection between dopamine, effort and the inflammatory response is an adaptive mechanism to help the body conserve energy. Trends in Cognitive Sciences published the theoretical framework developed by scientists at Emory

In spite of sufficient sleep tired all the time Who is repeated after at least eight hours of sleep in the course of a day, always tired, should investigate the causes. Because the backgrounds can be serious. Eight hours per night are still considered to be the common recommendation of doctors when it comes to

Depression, obesity and chronic pain could all be treated ‘by blocking the SAME protein’ Scientists blocked protein FKBP51 for the first time without also affecting others Hope will lead to treatment in humans; FKBP51 is also being tested in cancer FKBP51 has many functions from regulating glucose to stress management  e-mail 8 View comments Depression, obesity

Revealed: The alarming truth about breast implants 50,000 British women have every year Daisy Jones, 29, of Essex got a breast augmentation at 19 but regrets it now  One of her implants ruptures and she has suffered from chronic fatigue  Nicole Anderson, 31, of Lancashire, has bits of silicone inside her after rupture  Daisy Jones,

St. Jude Children’s Research Hospital scientists have discovered a subset of helper T cells that may help to redefine understanding and treatment of chronic, debilitating inflammatory disorders. The research appears today as an advance online publication in the journal Nature. The study focused on a family of helper T cells called Th17 cells. Th17 cells

New research published in Frontiers in Neurology finds that robotic arm rehabilitation in chronic stroke patients with aphasia, the loss of ability to understand or express speech, may promote speech and language function recovery. Robotic arm rehabilitation is a commonly-used intervention for treating impaired motor function in the arm, wrist, or shoulder subsequent to stroke.

Premenopausal women who have their ovaries surgically removed face an increased risk of developing chronic kidney disease, according to a Mayo Clinic study published on Wednesday, Sept. 19, in the Clinical Journal of the American Society of Nephrology. “This is the first study that has shown an important link between estrogen deprivation in younger women

Chronic pain may be an important contributor to suicide. Nearly 9 percent of people who died by suicide in 18 states from 2003 to 2014 had documentation of chronic pain in their incident records. Findings from the National Violent Death Reporting System (NVDRS) are published in Annals of Internal Medicine. More than 25 million adults