For patients with chronic liver disease, the onset of acute-on-chronic liver failure (ACLF) instantly alters the transplant question from 'if' to 'when'. 60 to 70% of patients with ACLF die within 3 months due to poor liver function and multiple organ failure. A timely liver transplant is the only way to save their lives. However,
Chronic fatigue syndrome / myalgic encephalomyelitis (CFS/ME) is a disabling disease, in which people have great difficulties in carrying out their daily activities. Despite its high prevalence, there are still no effective tools for its diagnosis, monitoring and treatment. To better understand and promote follow-up, as well as stratify fatigue in these patients, Vall d'Hebron,
Hypertension is a chronic disease that can lead to serious health problems. Patients with arterial hypertension are required to measure their blood pressure at home, which can have some drawbacks, such as forgetting to checkitor recordingthe values, errors in writing downthe figures,the inability to immediately notify health care staff about out-of-range blood pressure values, etc.
According to the World Health Organization (WHO), COVID-19 long-haulers are people who experience symptoms such as body ache, fatigue, shortness of breath, headache, difficulty concentrating, loss of taste or smell, or other health issues long after they test negative for the virus. It can be defined as having serious and prolonged symptoms three months after
Chronic Obstructive Pulmonary Disease (COPD) is a disease caused by cigarette smoking that reduces lung function and causes difficulty breathing. It is the third leading cause of death worldwide. Current treatments for COPD only affect symptoms, not progression. Identifying who is going to get COPD before they get it is key to figuring out how
Hospitalized COVID-19 patients with impaired first-phase ejection fraction were nearly 5 times more likely to die compared to patients with healthier measures of this early, often undetected sign of heart failure, according to new research published today in Hypertension, an American Heart Association journal. First-phase ejection fraction is a measure of the left ventricular ejection
An estimated 10% to 30% of people who get Covid-19 suffer from lingering symptoms of the disease, or what’s known as “long Covid.” Judy Dodd, who lives in New York City, is one of them. She spent nearly a year plagued by headaches, shortness of breath, extreme fatigue and problems with her sense of smell,
Primary sclerosing cholangitis (PSC) is a rare chronic inflammatory disease of the bile ducts and is difficult to treat, since its causes have not yet been adequately researched. Using RNA sequencing, an international research consortium led by Michael Trauner, Head of MedUni Vienna’s Division of Gastroenterology and Hepatology (Department of Medicine III), has now identified
New research from the University of Minnesota Medical School suggests that disease-driving B cells, a white blood cell, play a role in the development of non-alcoholic fatty liver disease (NAFLD) – the most common chronic liver condition in the U.S. Their findings could lead to targeted therapies for NAFLD, which currently affects a quarter of
We all feel physical pain in different ways, but people with nerve injuries often have a dysfunctional pain suppression system, making them particularly prone to discomfort. Now researchers have uncovered that virtual reality (VR) can reduce types of pain typically seen in patients with nerve injuries – and that VR can boost the dysfunctional pain
Music-based interventions have become a core ingredient of effective neurorehabilitation in the past 20 years thanks to the growing body of knowledge. In this theme issue of Neurorehabilitation, experts in the field highlight some of the current critical gaps in clinical applications that have been less thoroughly investigated, such as post-stroke cognition, traumatic brain injury,
Danjuma Adda, a Nigerian public health expert, became the president-elect of the World Hepatitis Alliance (WHA) in November last year. He is the first African to hold the position. Having been infected and lost his mother to hepatitis B, Adda's personal experience has fueled his passion and drive for a paradigm shift in fighting the
A drug approved for diabetes has now been shown to also help patients with diabetes lose on average 10 percent of their body weight, UT Southwestern reports in a landmark international study. Semaglutide, an injectable medication taken once a week, offers a nonsurgical way to reduce weight and treat obesity. It could help the more
The coronavirus disease 2019 (COVID-19) is a transmissible viral disease caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the pathogen responsible for the ongoing global pandemic. The virus was first detected in Wuhan, China, at the end of 2019 and to date has caused over 109 million infections worldwide. With over 2.4 million
Stiffness in our tissues causes tension in our cells. Research from the Buck Institute, the University Health Network (University of Toronto), Stanford University, and the University of Alberta shows that stiffness impacts the innate immune system by upping its metabolism. The findings suggest the cellular tension likely sets off an inflammatory loop that contributes to
Recently, a research team led by Profs. Liu Qingsong and Liu Jing from the Institute of Health & Medical Technology of the Hefei Institutes of Physical Science (HFIPS) discovered a potent and selective PI3Kδ inhibitor IHMT-PI3Kδ-372, effective against chronic obstructive pulmonary disease (COPD) in vivo. COPD is a chronic progressive respiratory disease characterized by airflow
TUESDAY, Oct. 13, 2020 — Among children who are hospitalized, pediatric chronic kidney disease (CKD) is associated with longer length of stay (LOS) and increased costs compared with other chronic illnesses, according to a study published online Oct. 12 in the American Journal of Kidney Diseases. Zubin J. Modi, M.D., from the University of Michigan
A new mass study of people living with chronic pain in the UK has demonstrated the links between pain and certain atmospheric weather conditions. Weather systems in the UK could cause chronic pain suffers to experience more or less pain on certain days as a result of certain pressure patterns and accompanying rain, humidity, and
A bit of stress is a normal part of our daily lives, which can even be good for us. Overcoming stressful events can make us more resilient. But when the stress is severe or chronic—for example caused by the breakdown of a marriage or partnership, death in the family or bullying—it needs to be dealt
A minimally invasive procedure to treat a common foot and ankle disorder can reduce pain, recovery time, and postsurgery complications while improving functional outcomes, according to a report published in the journal Foot and Ankle Surgery. The procedure treats insertional Achilles tendinopathy, a common and chronic orthopedic disorder in which patients experience pain at the
