12.14.18
Cohesin down-regulation drives hematopoietic stem cell aging
![](https://healthproblemsnews.com/wp-content/uploads/sites/5/2018/12/cfarmafoto5c13ba92743d8-150x150.jpg)
Aging is characterized by increases in inflammation and decreases in stem cell function. The relationship between these processes remains incompletely understood. Researchers of the Leibniz Institute on Aging (FLI) in Jena, Germany, identified a new role of the protein cohesin in mediating inflammatory signaling in hematopoietic stem cells (HSCs). Cohesin is required for gene regulation