The colon is a part of the digestive tract whose primary function is the absorption of water and nutrients from food. Colon cancer is a leading cause of mortality worldwide. Image Credit: crystal light/Shutterstock.com Recent evidence suggests that microbiota alternations in the gut are directly associated with colon cancer – it is found that oral
After Chadwick Boseman's tragic death from colon cancer at age 43, fans and celebrities lauded everything the "Black Panther" actor accomplished in his too-short life. Some people with cancer said they found the discourse was rooted in misconceptions about living with the disease, as if it's a sudden acute illness rather than a disability. Not
Combining a new class of drug with two other compounds can significantly shrink lung tumours in mice and human cancer cells, finds a new study led by the Francis Crick Institute and The Institute of Cancer Research, London. The study, published in Science Translational Medicine, looked at G12C KRAS inhibitors. This new type of drug
Adding immunotherapy in the form of durvalumab to chemotherapy improves overall survival in patients with extensive-stage small cell lung cancer, according to research presented today at the IASLC 2019 World Conference on Lung Cancer hosted by the International Association for the Study of Lung Cancer (IASLC). The research was presented by Dr. Luis Paz-Ares, from
A study published in Cell Reports Aug. 6 describes the generation of a new mouse model developed at Hollings Cancer Center that could lead to a better understanding of the cachexia syndrome. This wasting condition, characterized by excessive weight loss, has one of the highest incidence in pancreatic cancer patients. Denis Guttridge, Ph.D., Hollings Cancer
Known for its poor prognosis, lung adenocarcinoma is the most common type of lung cancer, responsible for about 4 of 10 diagnoses, according to the National Cancer Institute. Researchers on Mayo Clinic’s Florida campus can now distinguish between two pathways where this deadly cancer can develop. They say their discovery could help future patients. The
For years, doctors and scientists have known very little about why patients can receive drugs successfully for months, or even years, before developing a drug resistance. New University of Minnesota Medical School research proposes that there is a cellular as well as molecular cause to this phenomenon in colon cancer, with potential application to other
A combination of chemotherapy drugs during brain cancer surgery using a biodegradable paste, leads to long-term survival, researchers at the University of Nottingham have discovered. In a new study published in Clinical Cancer Research, scientists found a significant survival benefit in rat models with brain tumours when a combination of two chemotherapy drugs, (etoposide and
A research team headed by scientists at University of California San Diego School of Medicine and the Ludwig Institute for Cancer Research at UC San Diego has identified an enzyme involved in remodeling the plasma membrane of multiple cancer cell types that is critical to both survival of tumors and their uncontrolled growth. The finding,
A worldwide coalition of researchers and clinicians has agreed that light therapy is among the most effective interventions for the prevention of oral mucositis, painful ulcers in the mouth resulting from cancer therapy. The new guidelines from the Multinational Association of Supportive Care in Cancer (MASCC) and International Society of Oral Oncology (ISOO), published on
Research led by the University of Birmingham has found important new ways that the BRCA1 gene functions which could help develop our understanding of the development of ovarian and breast cancers. The research, published in Nature today (July 3rd), was led by experts at the University of Birmingham’s Birmingham Centre for Genome Biology and Institute
EPFL scientists have invented a new way to quantify — in real-time — glucose metabolism of cancerous tumors by making them bioluminesce. This new light probe is not radioactive and works on living organisms such as mice that carry the tumor cells. The technique requires tagged tumor cells, two jabs and a camera. The results
The incidence of colon and rectal cancer in adults younger than 50 years has increased substantially over the latest available 10-year period in several high-income countries, going against a decline or stabilisation trend in the incidence of colorectal cancers within the overall populations of high-income countries. This is according to an observational study published in
A multi-institutional clinical trial has given good results for a targeted therapy to treat a rare, aggressive blood cancer known as blastic plasmacytoid dendritic-cell neoplasm (BPDCN). Details on the trial, which supported Food and Drug Administration approval of the tagraxofusp therapy in December 2018, have been published in the New England Journal of Medicine. Diagnosed
Melanoma is one of the most aggressive types of skin cancer, but recent advances in targeted therapies have improved the prognosis for many patients. Unfortunately, for some patients these positive outcomes are not long lasting, due to the development of drug resistance and tumor recurrence. Moffitt Cancer Center researchers have discovered a mechanism by which
The origin of certain cancers in the sarcoma group is associated with a hitherto unknown interaction among different proteins. Findings now being presented create the opportunity to test new treatments of these forms of sarcoma. “We now know which mechanisms to shine the spotlight on,” says Pierre Åman, Professor of Tumor Biology at Sahlgrenska Academy,
Using data from computed tomography (CT) images, researchers may be able to predict which lung cancer patients will respond to chemotherapy, according to a new study published in the journal Radiology: Artificial Intelligence. Platinum-based chemotherapy is typically the first-line treatment of advanced-stage non-small cell lung cancer (NSCLC). However, only about one in four patients responds
Make us cow’s milk and beef sick? The German cancer research center (DKFZ) warns currently facing a newly discovered pathogen that is widely used in cow’s milk and beef products. Researchers found several relationships between the so-called BMMF-Eregern from milk and meat of animals of the bovine species and the Occurrence of colon cancer, and
Make us cow’s milk and beef sick? The German cancer research center (DKFZ) warns currently facing a newly discovered pathogen that is widely used in cow’s milk and beef products. Researchers found several relationships between the so-called BMMF-Eregern from milk and meat of animals of the bovine species and the Occurrence of colon cancer, and
We’re often told we are responsible for our own happiness. But in challenging situations, a UC Riverside study not only demonstrates the benefits of positive reframing — finding a “silver lining” — but also suggests our partners can be more adept at finding that silver lining than we are. A UCR psychology researcher says the
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