Tag: Colon Cancer

Chadwick Boseman worked through colon cancer. 3 other people with the illness talked to Insider about what that’s really like.

After Chadwick Boseman's tragic death from colon cancer at age 43, fans and celebrities lauded everything the "Black Panther" actor accomplished in his too-short life. Some people with cancer said they found the discourse was rooted in misconceptions about living with the disease, as if it's a sudden acute illness rather than a disability.  Not

Combination therapies could help treat fatal lung cancers: Combining a new class of drug with two other compounds can significantly shrink lung tumors in mice and human cancer cells

Combining a new class of drug with two other compounds can significantly shrink lung tumours in mice and human cancer cells, finds a new study led by the Francis Crick Institute and The Institute of Cancer Research, London. The study, published in Science Translational Medicine, looked at G12C KRAS inhibitors. This new type of drug

Durvalumab combined with chemotherapy improves overall survival in patients with lung cancer: First-line treatment reduces mortality risk by 27%

Adding immunotherapy in the form of durvalumab to chemotherapy improves overall survival in patients with extensive-stage small cell lung cancer, according to research presented today at the IASLC 2019 World Conference on Lung Cancer hosted by the International Association for the Study of Lung Cancer (IASLC). The research was presented by Dr. Luis Paz-Ares, from

Research advances to better target debilitating effects of cachexia syndrome: Cachexia research advances better target debilitating effects of cancer-related wasting syndrome

A study published in Cell Reports Aug. 6 describes the generation of a new mouse model developed at Hollings Cancer Center that could lead to a better understanding of the cachexia syndrome. This wasting condition, characterized by excessive weight loss, has one of the highest incidence in pancreatic cancer patients. Denis Guttridge, Ph.D., Hollings Cancer

Transfer of oncogene in colon cancer cells demonstrated

For years, doctors and scientists have known very little about why patients can receive drugs successfully for months, or even years, before developing a drug resistance. New University of Minnesota Medical School research proposes that there is a cellular as well as molecular cause to this phenomenon in colon cancer, with potential application to other

Targeted therapy proves effective against aggressive rare blood cancer: Clinical study treating BPDCN with tagraxofusp led to first FDA approval for the disease

A multi-institutional clinical trial has given good results for a targeted therapy to treat a rare, aggressive blood cancer known as blastic plasmacytoid dendritic-cell neoplasm (BPDCN). Details on the trial, which supported Food and Drug Administration approval of the tagraxofusp therapy in December 2018, have been published in the New England Journal of Medicine. Diagnosed

Mechanism of resistance to BRAF inhibitors in melanoma identified: A conserved stress response mechanism leads to BRAF inhibitor resistance through AP-1 activation

Melanoma is one of the most aggressive types of skin cancer, but recent advances in targeted therapies have improved the prognosis for many patients. Unfortunately, for some patients these positive outcomes are not long lasting, due to the development of drug resistance and tumor recurrence. Moffitt Cancer Center researchers have discovered a mechanism by which

Breakthrough in knowledge of how some sarcomas arise

The origin of certain cancers in the sarcoma group is associated with a hitherto unknown interaction among different proteins. Findings now being presented create the opportunity to test new treatments of these forms of sarcoma. “We now know which mechanisms to shine the spotlight on,” says Pierre Åman, Professor of Tumor Biology at Sahlgrenska Academy,

Radiomics predicts who will benefit from chemotherapy

Using data from computed tomography (CT) images, researchers may be able to predict which lung cancer patients will respond to chemotherapy, according to a new study published in the journal Radiology: Artificial Intelligence. Platinum-based chemotherapy is typically the first-line treatment of advanced-stage non-small cell lung cancer (NSCLC). However, only about one in four patients responds

New study warns: cow’s milk and beef is a cancer trigger

Make us cow’s milk and beef sick? The German cancer research center (DKFZ) warns currently facing a newly discovered pathogen that is widely used in cow’s milk and beef products. Researchers found several relationships between the so-called BMMF-Eregern from milk and meat of animals of the bovine species and the Occurrence of colon cancer, and

New study warns: cow’s milk and beef is a cancer risk factor

Make us cow’s milk and beef sick? The German cancer research center (DKFZ) warns currently facing a newly discovered pathogen that is widely used in cow’s milk and beef products. Researchers found several relationships between the so-called BMMF-Eregern from milk and meat of animals of the bovine species and the Occurrence of colon cancer, and

Coping with cancer: Partners can reframe challenging situations

We’re often told we are responsible for our own happiness. But in challenging situations, a UC Riverside study not only demonstrates the benefits of positive reframing — finding a “silver lining” — but also suggests our partners can be more adept at finding that silver lining than we are. A UCR psychology researcher says the

Advancing therapy by measuring the ‘games’ cancer cells play

Cleveland: Despite rapid advances in targeted therapies for cancer, tumors commonly develop resistance to treatment. When resistance emerges, tumor cells continue to grow unchecked, despite all attempts to slow cancer progression. While mutations in cancer cells significantly affect drug sensitivity, it is increasingly recognized that ecological interactions between cells can also play a role. Jacob