Tag: Coronavirus Disease

What are the risk factors for severe disease in children hospitalized for SARS-CoV-2 infection?

The coronavirus disease 2019 (COVID-19) pandemic has largely passed children by, with fewer infections and a minute proportion of deaths in this age group. However, some adverse outcomes do occur, such as the multisystem inflammatory syndrome in children (MIS-C). Study: Risk factors for severe PCR-positive SARS-CoV-2 infection in hospitalized children: a multicenter cohort study. Image

Sexually dimorphic placental antibody transfer during SARS-CoV-2 infection

Sex-based differences in COVID-19 disease transmission, severity, and mortality have been reported since the early stages of the pandemic in infants, with the underlying mechanism accounting for these differences not yet fully understood. In a paper recently published in the journal Science Translational Medicine by Bordt et al. (October 19th, 2021), maternal SARS-CoV-2 infections are

SARS-CoV-2 infection aided by antibody-dependent enhancement

The coronavirus disease 2019 (COVID-19) pandemic spread rapidly around the world, leading to lockdowns, social distancing measures, and millions of deaths. However, with the help of mass vaccination campaigns and monoclonal antibody treatments, the transmission of the disease is beginning to slow down. Vaccines rely on the immune systems ability to produce specific antibodies –