Building on recent work, researchers including Danny Winder, director of the Vanderbilt Center for Addiction Research have developed a clear picture of how particular circuitry in the brain may be involved in drug- and alcohol-seeking behavior. They derived a control network for the bed nucleus of the stria terminalis, a part of a larger brain
The coronavirus disease 2019 (COVID-19) pandemic has claimed well over 2.4 million lives, but its long-term sequelae are still being identified. The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) produces an infection that may be associated with a wide spectrum of disease, from asymptomatic to critical or terminal respiratory failure or multi-organ dysfunction. A new
Anxiety is an adaptive response that is of great benefit to all life forms. It triggers fear learning, i.e., survival instincts that alert an organism to its surroundings and the dangers that prevail in it. However, extreme anxiety that is inappropriate to a circumstance and is prolonged is a negative emotion, labeled as a social
A research team led by Michael Fox, a professor at the Fralin Biomedical Research Institute at VTC, has identified the type of brain cell that produces collagen 19, a protein that is crucial for the formation of inhibitory circuits in the brain. The study, published in the Journal of Neuroscience, depicts a previously unknown molecular
Adult rats that had been exposed before birth and during nursing to a mixture of chemicals found in a wide range of consumer products have a smaller medial prefrontal cortex (mPFC) and perform worse on an attention-switching task than rats not exposed to the chemicals early in life. These findings, published in JNeurosci, demonstrate a
A breakthrough in brain research has promising implications for health and may lead to new answers about depression, attention-deficit hyperactivity disorder (ADHD) and Parkinson’s disease. In a recent study, University of Victoria cognitive neuroscientist Clay Holroyd—with post-doctoral fellow José Ribas-Fernandes and Ph.D. student Danesh Shahnazian from UVic, and colleagues Tom Verguts and Massimo Silvetti from
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