In a new study published in the Cell Research, Chen-Yu Zhang’s group at Nanjing University reports “In vivo self-assembled small RNA is the new generation of RNAi therapeutics.” The development of RNAi therapy has undergone two major stages, direct injection of synthetic siRNAs and delivery with artificial vehicles; neither have realized the full therapeutic potential
In a retrospective analysis of cesarean deliveries from 2015 through 2020, a team of doctors from the Colorado Fetal Care Center at Children’s Hospital Colorado (Children’s Colorado) found that using a wound infusion pump in combination with enhanced recovery efforts such as removing urinary catheters earlier and walking around the same day of surgery can
Highmark Health, in collaboration with Google Cloud, today announced its Living Health model and corresponding platform that aims to reshape how healthcare is delivered to be a more coordinated, personalized and technology-enabled experience. Throughout the companies’ six-year strategic partnership, Highmark will support its Living Health model through the development of the Living Health Dynamic Platform,
Researchers at ETH Zurich have developed a method for concentrating and releasing drugs in the brain with pinpoint accuracy. This could make it possible in the future to deliver psychiatric and cancer drugs and other medications only to those regions of the brain where this is medically desirable. Today, this is practically impossible—drugs traveling through
A Rutgers-led team has created a smart drug delivery system that reduces inflammation in damaged nervous tissues and may help treat spinal cord injuries and other neurological disorders. The system, which uses extremely thin biomaterials implanted in the body, also protects nerve fibers (axons) that connect nerve cells in injured neural tissues, according to a
Editor’s note: Due to high demand for their produce boxes right now, Misfits Market is currently not accepting first-time orders and has set up a waitlist to get new subscribers in on the ugly produce party as soon as possible. Subscribers may also experiencedelays as the company works through supply chain issues related to COVID-19.
The maturation of skin microbial communities during childhood is important for the skin health of children and development of the immune system into adulthood, but only a few studies have analyzed the microbiota in young children. In a new study, investigators in China found that bacterial genera in children were more similar to those of
The older I get, the more my daydreams change. I used to fantasize about strolling down white sand beaches in remote island locations. Now? I’d be happy to have two hours of uninterrupted reading time. Ever since I following doing the keto diet, a new dream took shape. In it, I walked into a room
Cancer tissue cells are divided into two major groups: cancer cells and cancer stem cells (CSCs). CSCs are related to cancer progression and dissemination, so it’s necessary to eradicate CSCs in order to cure cancer. However, because CSCs are resistant to chemotherapy and radiotherapy, cancer is refractory. A research group from Osaka University, in collaboration
Stroke is the most common cause of adult disability. This is due not only to the high incidence of stroke, but also because spontaneous recovery is often incomplete and no drugs are available that hasten recovery. Mesencephalic astrocyte-derived neurotrophic factor MANF is neuroprotective when administered before experimental stroke in rats. A massive immune response mediated
(HealthDay)—Introducing the Comprehensive Primary Care Initiative (CPC), a health care delivery model developed by the Centers for Medicare and Medicaid Services (CMS), improves primary care delivery but does not reduce Medicare spending enough to cover care management fees, according to a study published online May 23 in Health Affairs. Deborah Peikes, Ph.D., from Mathematica Policy
Amniotic fluid can be routinely obtained without harming the mother or the fetus. Researchers have previously demonstrated that amniotic fluid contains mesenchymal stem cells with great differentiation and regenerative potential. Importantly, amniotic fluid stem cells are immune privileged, non-carcinogenic and their potential clinical applications such as cell-replacement therapies to treat bone defects, ischemic stroke, bladder
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